Skip to Content
Merck
All Photos(3)

Key Documents

1.00030

Supelco

Acetonitrile

≥99.9% (GC), gradient grade, suitable for HPLC, Reag. Ph Eur, LiChrosolv®

Synonym(s):

ACN, Cyanomethane, Ethyl nitrile, Methyl cyanide

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
CH3CN
CAS Number:
Molecular Weight:
41.05
Beilstein:
741857
MDL number:
UNSPSC Code:
12191502
EC Index Number:
200-835-2
NACRES:
NA.03
grade:
gradient grade
Assay:
≥99.9% (GC)
technique(s):
HPLC: suitable
bp:
81-82 °C (lit.)
vapor pressure:
72.8 mmHg ( 20 °C)
97 hPa ( 20 °C)

Product Name

Acetonitrile, gradient grade for liquid chromatography LiChrosolv® Reag. Ph Eur

grade

gradient grade

Quality Level

Agency

reag. Ph. Eur.

vapor density

1.41 (vs air)

vapor pressure

72.8 mmHg ( 20 °C)
97 hPa ( 20 °C)

product line

LiChrosolv®

Assay

≥99.9% (GC)

form

liquid

autoignition temp.

524 °C
973 °F

expl. lim.

16 %

technique(s)

HPLC: suitable

impurities

≤0.0002 meq/g Acidity
≤0.0002 meq/g Alkalinity
≤0.02% Water

evapn. residue

≤2.0 mg/L

color

APHA: ≤10

transmittance

193 nm, ≥60%
195 nm, ≥80%
230 nm, ≥98%

refractive index

n20/D 1.344 (lit.)

bp

81-82 °C (lit.)

mp

−45 °C (lit.)

transition temp

flash point 2 °C

density

0.786 g/mL at 25 °C (lit.)

format

neat

storage temp.

2-30°C

SMILES string

CC#N

InChI

1S/C2H3N/c1-2-3/h1H3

InChI key

WEVYAHXRMPXWCK-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

LiChrosolv® solvents were specially formulated to meet the demanding needs of analytical HPLC applications. With exceptional UV transmittance, minimal particle count, and controlled acidity and alkalinity, our solvents ensure reproducible separations every time. The low evaporation residue level further enhances their performance, making them the ideal choice for high-quality results. The product line includes both "gradient grade" and "isocratic grade" solvents, specifically designed to reduce the gradient effect during separations. This tailored approach allows for optimal consistency and accuracy in your analytical processes, helping you achieve the best possible outcomes in your chromatography work.

Now Available with Data Matrix Code
This high-quality HPLC-grade solvent now features a unique Data Matrix Code on its label, providing digital access to essential product information such as batch number, product number, and expiry date. Unlike standard barcodes, our DMCs feature a unique serial number for each bottle, enabling you to monitor and trace every bottle individually. With standard barcodes, all bottles from the same batch look identical. Our solution gives you true bottle-level traceability for greater control and compliance in the lab.
Know more about our data matrix code-labeled HPLC-grade solvents.

Application

  • Reversed-Phase HPLC: Commonly used as a mobile phasecomponent for the separation of a wide range of compounds, includingpharmaceuticals, environmental pollutants, and biomolecules.
  • Gradient Elution: Ideal for gradient elutiontechniques, enhancing the resolution and separation efficiency of complexmixtures.
  • Pharmaceutical Analysis: Frequently employed in theanalysis of active pharmaceutical ingredients (APIs) and their impurities,ensuring compliance with regulatory standards.
  • Biological Sample Analysis: Used for the analysis ofproteins, peptides, and metabolites in biological samples, facilitatingaccurate quantification and identification.
  • Environmental Monitoring: Applied in the HPLCanalysis of environmental samples to detect and quantify contaminants in water,soil, and air.

Features and Benefits

  • High Purity: Formulated with minimal impurities,ensuring reliable and reproducible results essential for sensitive analyticalapplications.
  • Excellent UV Transparency: Provides optimal UVtransmittance, facilitating accurate detection and enhancing sensitivity inHPLC analyses.
  • Low Evaporation Residue: Minimizes contaminationrisk, leading to cleaner separations and improved analytical reliability.Batch-to-Batch.
  • Consistency: Ensures uniform qualityand performance across different production batches, enhancing reproducibilityand confidence in analytical results.

Preparation Note

Microfiltered by 0.2 μm filter

Other Notes

Explore various lab safety accessories and equipment for safe handling of solvents to increase your safety level from the first usage.

Legal Information

LICHROSOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

35.6 °F - closed cup

Flash Point(C)

2.0 °C - closed cup


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service