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Merck

1.00397

N,N-Dimethylformamide

for peptide synthesis

Synonym(s):

DMF, N,N-Dimethylmethanamide, Formic acid dimethylamide, DMF, NSC 5356

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About This Item

Linear Formula:
HCON(CH3)2
CAS Number:
Molecular Weight:
73.09
UNSPSC Code:
12352111
NACRES:
NA.22
EC Index Number:
200-679-5
MDL number:
Beilstein/REAXYS Number:
605365
assay:
≥99.9% (GC)
application(s):
peptide synthesis
bp:
153 °C (lit.)
vapor pressure:
2.7 mmHg ( 20 °C)

Product Name

N,N-Dimethylformamide, for peptide synthesis

InChI

1S/C3H7NO/c1-4(2)3-5/h3H,1-2H3

SMILES string

[H]C(=O)N(C)C

InChI key

ZMXDDKWLCZADIW-UHFFFAOYSA-N

vapor density

2.5 (vs air)

vapor pressure

2.7 mmHg ( 20 °C)

assay

≥99.9% (GC)

form

liquid

autoignition temp.

833 °F

potency

3010 mg/kg LD50, oral (Rat)
1500 mg/kg LD50, skin (Rabbit)

expl. lim.

15.2 %

dilution

(for synthesis)

impurities

≤0.0002 meq/g Alkalinity
≤0.0005 meq/g Acidity
≤10 ppm Amines (Dimethylamine)
≤300 ppm Water

color

APHA: ≤10

refractive index

n20/D 1.430 (lit.)

pH

7 (20 °C, 200 g/L in H2O)

bp

153 °C (lit.)

mp

−61 °C (lit.)

transition temp

flash point 57.5 °C

solubility

soluble 1000 g/L

density

0.944 g/mL (lit.)

application(s)

peptide synthesis

storage temp.

2-30°C

Quality Level

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Analysis Note

Purity (GC): ≥ 99.9 %
Identity (IR): conforms
Color: ≤ 10 Hazen
Acidity: ≤ 0.0005 meq/g
Alkalinity: ≤ 0.0002 meq/g
Amines (Dimethylamine): ≤ 10 ppm
Evaporation residue: ≤ 10
Water: ≤ 300 ppm

Application

Solvent for many hydrophobic organic compounds.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Flam. Liq. 3 - Repr. 1B

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

135.5 °F - closed cup

flash_point_c

57.5 °C - closed cup


Certificates of Analysis (COA)

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