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1.04008

Formamide

EMPLURA®

Synonym(s):

Formic acid amide, Methane amide, Amide C1, Formic amide

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About This Item

Linear Formula:
HCONH2
CAS Number:
75-12-7
Molecular Weight:
45.04
UNSPSC Code:
12352111
NACRES:
NA.21
EC Index Number:
200-842-0
MDL number:
MFCD00007941
Beilstein/REAXYS Number:
505995
eCl@ss:
32150917
Assay:
≥99% (N)
Technique(s):
hybridization: suitable
Bp:
210 °C (lit.)
Vapor pressure:
0.08 mmHg ( 20 °C), 30 mmHg ( 129 °C)
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vapor density

1.55 (vs air)

Quality Segment

vapor pressure

0.08 mmHg ( 20 °C), 30 mmHg ( 129 °C)

product line

EMPLURA®

assay

≥99% (N)

form

liquid

autoignition temp.

932 °F

potency

5325 mg/kg LD50, oral (Rat), 17000 mg/kg LD50, skin (Rabbit)

expl. lim.

2.7-19.0 % (v/v)

technique(s)

hybridization: suitable

impurities

≤0.3% Water (Karl Fischer)

refractive index

n20/D 1.447 (lit.)

pH

8-10 (20 °C, 200 g/L in H2O)

bp

210 °C (lit.)

mp

2-3 °C (lit.)

transition temp

flash point 175 °C

density

1.134 g/mL at 25 °C (lit.)

storage temp.

15-25°C

SMILES string

NC=O

InChI

1S/CH3NO/c2-1-3/h1H,(H2,2,3)

InChI key

ZHNUHDYFZUAESO-UHFFFAOYSA-N

Application

Formamide destabilizes nucleic acid duplexes and may be used, typically, at a concentration of 50%, in hybridization protocols requiring lower hybridization temperatures.

Analysis Note

Assay (N; Kjeldahl): ≥ 99.0 %
Identity (IR): passes test
Density (d 20 °C/ 4 °C): 1.132 - 1.135
Water (according to Karl Fischer): ≤ 0.3 %

Legal Information

EMPLURA is a registered trademark of Merck KGaA, Darmstadt, Germany

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Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Codes

H351,H360D,H373

Hazard Classifications

Carc. 2 - Repr. 1B - STOT RE 2 Oral

Target Organs

Blood

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

Flash Point (°F)

305.6 °F

Flash Point (°C)

152 °C

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