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Merck

1.04239

Glutardialdehyde solution 25%

for electron microscopy

Synonym(s):

Glutaraldehyde solution, Glutaric dialdehyde solution, Pentane-1,5-dial

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About This Item

Linear Formula:
OHC(CH2)3CHO
CAS Number:
111-30-8
Molecular Weight:
100.12
NACRES:
NA.21
UNSPSC Code:
12352114
Beilstein/REAXYS Number:
605390
MDL number:
MFCD00007025
Technique(s):
electron microscopy: suitable
Application(s):
diagnostic assay manufacturing
hematology
histology
Bp:
100.5 °C/1013 hPa
Vapor pressure:
0.27 hPa ( 20 °C)

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Product Name

Glutardialdehyde solution 25%, for electron microscopy

SMILES string

[H]C(CCCC([H])=O)=O

InChI

1S/C5H8O2/c6-4-2-1-3-5-7/h4-5H,1-3H2

InChI key

SXRSQZLOMIGNAQ-UHFFFAOYSA-N

vapor pressure

0.27 hPa ( 20 °C)

form

liquid

concentration

23.5-26.5% (alkalimetric)

technique(s)

electron microscopy: suitable

color

colorless

pH

>3.0 (20 °C in H2O)

bp

100.5 °C/1013 hPa

mp

-6 °C

density

1.06 g/cm3 at 20 °C

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

2-8°C

Quality Level

200

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Analysis Note

Assay (alkalimetric): 23.5 - 26.5 %
pH-value: ≥ 3.0
Density (d 20 °C/ 4 °C): 1.060 - 1.065
Absorbance A (235 nm; 1:200 deluted with water; 1 cm): ≤ 0.3

General description

Glutardialdehyde solution 25% - for electron microscopy, is a fixing agent for specimens destined for morphological and enzyme histochemical analysis. The 25% Glutardialdehyde solution is used for the fixation of specimen of human origin for semi-thin cuttings and electron microscopy. It is diluted with phosphate buffer(Potassium dihydrogen phosphate for analysis EMSURE® ISO (Product number 1.04873) or di-Sodium hydrogen phosphate anhydrous for analysis EMSURE® ACS,Reag. Ph Eur (Product number 1.06586)
to achieve the corresponding working concentration. Alternatively, especially sensitive material used for enzyme histochemistry, will be fixed with glutardialdehyde according to P.J. Anderson, purified and filled into ampoules under nitrogen (Product number 1.12179). Sensitive enzymes e.g. endogenous peroxidase can often only be visualized in this way. It is an IVD registered product and CE certified, thus can be used for clinical diagnostic purposes. For more details, please see instructions for use (IFU). The IFU can be downloaded from this webpage.

Legal Information

EMSURE is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

supp_hazards

EUH071

Storage Class

8A - Combustible, corrosive hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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