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Merck

1079

N-Acetyl-D-glucosamine

An acceptor substrate for galactosyltransferases. Inhibits the lectin WGA and β-N-acetylhexosaminidase (Ki = 430 µM). When added to a medium, it improves the recovery of Haemophilus influenza from sputum.

Synonym(s):

N-Acetyl-D-glucosamine, NAG, GlcNAc

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About This Item

Empirical Formula (Hill Notation):
C8H15NO6
CAS Number:
7512-17-6
Molecular Weight:
221.21
UNSPSC Code:
12352201
NACRES:
NA.21
MDL number:
MFCD00061615

Product Name

N-Acetyl-D-glucosamine, An acceptor substrate for galactosyltransferases. Inhibits the lectin WGA and β-N-acetylhexosaminidase (Ki = 430 µM). When added to a medium, it improves the recovery of Haemophilus influenza from sputum.

SMILES string

N(C1C(OC(C(C1O)O)CO)O)C(=O)C

InChI

1S/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)

InChI key

OVRNDRQMDRJTHS-UHFFFAOYSA-N

assay

≥98% (HPLC)

form

powder

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

off-white to beige
 white to off-white

solubility

water: 10 mg/mL

shipped in

ambient

storage temp.

2-8°C

Quality Level

100

Related Categories

Disclaimer

Toxicity: Standard Handling (A)

General description

Acceptor substrate for galactosyltransferases. Lectin inhibitory amino sugar. When added to the medium, it improves the recovery of Haemophilus influenza from sputum. A competitive inhibitor of β-N-acetylhexosaminidase (Ki = 430 µM).
An acceptor substrate for galactosyltransferases. Inhibits the lectin WGA and β-N-acetylhexosaminidase (Ki = 430 µM). When added to a medium, it improves the recovery of Haemophilus influenza from sputum.

Other Notes

Sakai, K., et al. 1994. Appl. Environ. Microbiol. 60, 2911.
Moller, L.V., et al. 1993. J. Clin. Microbiol. 31, 1952.

Preparation Note

Following initial thaw, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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K Sakai et al.
Applied and environmental microbiology, 60(8), 2911-2915 (1994-08-01)
Thermostable exochitinase was purified to homogeneity from the culture fluid of Bacillus stearothermophilus CH-4, which was isolated from agricultural compost containing shrimp and crabs. The enzyme was a single polypeptide with a molecular mass of 74 kDa, and the N-terminal
L V Möller et al.
Journal of clinical microbiology, 31(7), 1952-1954 (1993-07-01)
A modified selective medium supplemented with N-acetyl-D-glucosamine (NAG), hemin, and NAD plus two cefsulodin disks, for primary isolation of nonencapsulated Haemophilus influenzae from sputum of patients with cystic fibrosis, is described. Isolation of H. influenzae from this medium, designated NAG

Global Trade Item Number

SKUGTIN
1079-1KG04054839027079

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