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1.08101

Tetrahydrofuran

for liquid chromatography LiChrosolv® Reag. ChP

Synonym(s):

THF, Tetramethylene oxide, Oxolane, Butylene oxide, Butylene oxide, Oxolane, Tetramethylene oxide

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About This Item

Linear Formula:
(CH2)3CH2O
CAS Number:
109-99-9
Molecular Weight:
72.11
NACRES:
NA.03
EC Index Number:
203-726-8
UNSPSC Code:
12191504
MDL number:
MFCD00005356
Beilstein/REAXYS Number:
102391
Assay:
≥99.9% (GC)
Technique(s):
HPLC: suitable
Bp:
65-67 °C (lit.)
Vapor pressure:
114 mmHg ( 15 °C), 143 mmHg ( 20 °C)
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Product Name

Tetrahydrofuran, for liquid chromatography LiChrosolv® Reag. ChP

Quality Segment

agency

reag. ChP

vapor density

2.5 (vs air)

vapor pressure

114 mmHg ( 15 °C), 143 mmHg ( 20 °C)

description

isocratic

product line

LiChrosolv®

assay

≥99.9% (GC)

form

liquid

autoignition temp.

610 °F

expl. lim.

1.8-11.8 %

technique(s)

HPLC: suitable

impurities

≤0.0002 meq/g Acidity, ≤0.0002 meq/g Alkalinity, ≤0.02% Peroxide, ≤0.02% Water

evapn. residue

≤1.0 mg/L

transmittance

218 nm, ≥30%, 230 nm, ≥35%, 250 nm, ≥65%, 280 nm, ≥95%

refractive index

n20/D 1.407 (lit.)

pH

7-8 (20 °C, 200 g/L in H2O)

bp

65-67 °C (lit.)

mp

−108 °C (lit.)

transition temp

flash point -20 °C

density

0.889 g/mL at 25 °C (lit.)

absorbance ratio

/290 ≤0.02, 280 nm ≤0.05, 254 nm ≤0.20, 240 nm ≤0.35, 300/0.01 nm

storage temp.

2-30°C

SMILES string

C1CCOC1

InChI

1S/C4H8O/c1-2-4-5-3-1/h1-4H2

InChI key

WYURNTSHIVDZCO-UHFFFAOYSA-N

General description

LiChrosolv® solvents have high degree of UV transmittance, low particle count, low acidity and alkalinity and low evaporation residue level. This makes them ideal for reproducible separations.

Application

Used as a solvent in chromatography applications.
Also featured in USP monograph methods for regulated pharmaceutical instrumental analysis.

Features and Benefits

  • packaged in glass bottles
  • offers high resolution, sensitivity and optimized peak baseline separation

Preparation Note

Product filtered through a 0.2 μm filter

Analysis Note

Purity (GC): ≥ 99.9 %
Identity (IR): conforms
Evaporation residue: ≤ 1.0 mg/l
Water: ≤ 0.02 %
Acidity: ≤ 0.0002 meq/g
Alkalinity: ≤ 0.0002 meq/g
Peroxide: ≤ 0.02 %
Transmission (at 218 nm): ≥ 30 %
Transmission (at 230 nm): ≥ 35 %
Transmission (at 250 nm): ≥ 65 %
Transmission (at 280 nm): ≥ 95 %
Filtred by 0.2µm filter

Other Notes

Explore various lab safety accessories and equipment for safe handling of solvents to increase your safety level from the first usage.

Legal Information

LICHROSOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

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Signal Word

Danger

Target Organs

Central nervous system, Respiratory system

supp_hazards

EUH019

Storage Class

3 - Flammable liquids

Flash Point (°F)

-6.2 °F - closed cup

Flash Point (°C)

-21.2 °C - closed cup

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - STOT SE 3

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