1.09334
LiChrosorb® RP-18 (10 µm) HPLC Columns
HPLC sorbent
Synonym(s):
TM=["LiChrosorb"] C18 sorbent for HPLC
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About This Item
UNSPSC Code:
41115709
NACRES:
SB.52
Particle size:
10 μm
Matrix active group:
C18 bonding phase
Pore size:
100 Å pore size
Matrix:
fully porous particle
Product Name
LiChrosorb® RP-18 (10 µm),
material
stainless steel column
agency
suitable for USP L1
product line
LiChrosorb®
feature
endcapped: no
parameter
60 °C max. temp.
technique(s)
HPLC: suitable, mass spectrometry (MS): suitable (Low)
matrix
fully porous particle
matrix active group
C18 bonding phase
particle size
10 μm
pore size
100 Å pore size
operating pH range
2-7.5
bulk density
200‑400 kg/m3
separation technique
reversed phase
storage temp.
no temp limit
Application
- High-performance liquid chromatographic determination of the antifungal drug fluconazole in plasma and saliva of human immunodeficiency virus-infected patients.: This study highlights a method using RP-18 for the determination of fluconazole, demonstrating the column′s effectiveness in bioanalytical contexts (Beijnen JH et al., 1995).
- Determination of serum aluminium using an ion-pair reversed-phase high-performance liquid chromatographic-fluorimetric system with lumogallion.: This research utilizes RP-18 to analyze serum aluminum, showcasing its utility in trace metal analysis in clinical samples (Ong CN et al., 1995).
- A radiochemical high-performance liquid chromatographic method for the analysis of 2-fluoro-2-deoxy-D-glucose-derived metabolites in human chondrocytes.: The method developed employs RP-18, underscoring its role in the radiochemical analysis of complex biological matrices (Greiling H et al., 1993).
- Systematic approach to the determination of cephalosporins in biological fluids by reversed-phase liquid chromatography.: This study demonstrates the application of RP-18 in the pharmacokinetic analysis of cephalosporins, further proving the column′s broad applicability in pharmaceutical analyses (Juge F et al., 1983).
- Simultaneous determination of 3,4-dihydroxyphenylalanine, 5-hydroxytryptophan, dopamine, 4-hydroxy-3-methoxyphenylalanine, norepinephrine, 3,4-dihydroxyphenylacetic acid, homovanillic acid, serotonin, and 5-hydroxyindoleacetic acid in rat cerebrospinal fluid and brain by high-performance liquid chromatography with electrochemical detection.: This research uses RP-18 to simultaneously quantify multiple neurotransmitters, highlighting its sensitivity and specificity for neurochemical analysis (Huot S et al., 1982).
Analysis Note
Theoretical Plates (N/m) (Toluene): ≥ 25000
stability testing (performance): passes test
particle size (Malvern) (d10): 8.7 - 10.0 µm
particle size (Malvern) (d50): 12.0 - 14.0 µm
particle size (Malvern) (d90): 17.5 - 20.5 µm
stability testing (performance): passes test
particle size (Malvern) (d10): 8.7 - 10.0 µm
particle size (Malvern) (d50): 12.0 - 14.0 µm
particle size (Malvern) (d90): 17.5 - 20.5 µm
Legal Information
LiChrosorb is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class
11 - Combustible Solids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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