1.16129
LiChrospher® 100 RP-8 (5 µm) HPLC Columns
HPLC sorbent
Synonym(s):
TM=["LiChrospher"] C8 sorbent for HPLC
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About This Item
UNSPSC Code:
41115709
NACRES:
SB.52
Particle size:
5 μm
Matrix active group:
C8 bonding phase
Pore size:
100 Å pore size
Matrix:
fully porous particle
Product Name
LiChrospher® 100 RP-8 (5 µm),
material
stainless steel column
agency
suitable for USP L7
product line
LiChrospher®
feature
endcapped: no
extent of labeling
12.5% Carbon loading
parameter
60 °C max. temp.
technique(s)
HPLC: suitable, mass spectrometry (MS): suitable (Low - Medium)
surface area
350 m2/g
matrix
fully porous particle
matrix active group
C8 bonding phase
particle size
5 μm
pore size
100 Å pore size
operating pH range
2-7.5
bulk density
200‑400 kg/m3
separation technique
reversed phase
storage temp.
no temp limit
General description
LiChrospher® RP-8 is a reliable and versatile traditionally produced spherical silica gel carrier with C-8 reversed phase properties. It is well suited for the separation of neutral, acidic and weak basic compounds.
Application
- Development and validation of a HPLC-UV method for the determination in didanosine tablets.: This study presents a validated HPLC-UV method optimized using LiChrospher® 100 RP-8 (5 µm) for analyzing didanosine in tablet formulations, offering a reliable tool for quality control in pharmaceutical environments (de Oliveira et al., 2005).
- Determination of steroid hormones in oral contraceptives by high-performance liquid chromatography.: Utilizes LiChrospher® 100 RP-8 (5 µm) to effectively separate and quantify steroid hormones in oral contraceptive pills, demonstrating the column′s applicability in complex pharmaceutical analyses (Inês et al., 2002).
- Determination of fluoroquinolone residues in animal tissues by liquid chromatography.: Explores the use of LiChrospher® 100 RP-8 (5 µm) for the sensitive detection of fluoroquinolone residues in animal tissues, highlighting its potential for food safety and veterinary medicine applications (Posyniak et al., 1999).
- Rapid and simple determination of oxytetracycline in chicken products.: Demonstrates the column′s efficiency in rapidly quantifying oxytetracycline residues in chicken, ensuring compliance with food safety standards (Furusawa, 1999).
- Crocheted ETFE-reactor for on-line post-column photoderivatization of diclofenac in high-performance liquid chromatography.: Describes an innovative application involving LiChrospher® 100 RP-8 (5 µm) in a post-column reactor setup to enhance the detection sensitivity of diclofenac, underlining the column′s versatility in advanced analytical techniques (Kuhlmann et al., 1997).
Analysis Note
Application test: passes test
Pressure: ≤ 45 bar
Theoretical Plates (N/m) (Toluene): ≥ 60000
Capacity factor (Toluene): ≥ 0.7
stability testing (performance): passes test
separation factor (PTH-Lysine/PHB-Propyl-Ester, selectivity test): 1.20 - 1.55
separation factor (Naphthalene/Digitoxigenin, selectivity test): 3.5 - 4.7
separation factor (PTH-Lysine/Digitoxigenin, selsctivity test): 1.70 - 2.25
Particle Size (d10): 4.8 - 5.5 µm
Particle Size (d50): 6.5 - 7.5 µm
Particle Size (d90): 9.0 - 10.5 µm
Pressure: ≤ 45 bar
Theoretical Plates (N/m) (Toluene): ≥ 60000
Capacity factor (Toluene): ≥ 0.7
stability testing (performance): passes test
separation factor (PTH-Lysine/PHB-Propyl-Ester, selectivity test): 1.20 - 1.55
separation factor (Naphthalene/Digitoxigenin, selectivity test): 3.5 - 4.7
separation factor (PTH-Lysine/Digitoxigenin, selsctivity test): 1.70 - 2.25
Particle Size (d10): 4.8 - 5.5 µm
Particle Size (d50): 6.5 - 7.5 µm
Particle Size (d90): 9.0 - 10.5 µm
Legal Information
LiChrospher is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class
11 - Combustible Solids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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