manufacturer/tradename
Upstate®
technique(s)
activity assay: suitable (kinase)
NCBI accession no.
UniProt accession no.
shipped in
dry ice
Gene Information
human ... PRKCA(5578)
Analysis Note
Routinely evaluated as a substrate for PKC Epsilon (14-236), PKC Zeta (14-235) and MST2 activity (14-417).
Biochem/physiol Actions
Protein Target: PKC
Target Sub-Family: AGC
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Physical form
Lyophilized powder
Preparation Note
Lyophilized: 2 years at -20°C; Rehydrated: 6 months at -20°C.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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Expression, purification, and characterization of protein kinase C-epsilon
Schaap, D. and Parker, P. J.
The Journal of Biological Chemistry, 265, 7301-7307 (1990)
H L Lai et al.
The Journal of biological chemistry, 272(8), 4970-4977 (1997-02-21)
We have previously reported that phosphorylation of adenylyl cyclase type VI (AC6) may result in the suppression of adenylyl cyclase activity during desensitization of the A2a-adenosine receptor-mediated cAMP response (A2a desensitization) in rat pheochromocytoma PC12 cells. In the present study
D Schaap et al.
FEBS letters, 243(2), 351-357 (1989-01-30)
PKC-epsilon was isolated from a murine brain cDNA library. The clone, lambda 61PKC-epsilon, encoded a polypeptide of 737 amino acids that is homologous to other PKCs. Northern analysis showed that the 7 kb mRNA for this cDNA is widely expressed.
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