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Merck

1.24542

Nicotinamide adenine dinucleotide free acid

for biochemistry NAD

greener alternative

Greener Alternative

Synonym(s):

Nicotinamide adenine dinucleotide free acid, NAD free acid, DPN

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About This Item

Empirical Formula (Hill Notation):
C21H27N7O14P2
CAS Number:
Molecular Weight:
663.43
UNSPSC Code:
12352107
EC Index Number:
200-184-4
NACRES:
NB.21
MDL number:
eCl@ss:
39200202
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Quality Segment

form

solid

sustainability

Sustainability features

pH

2.5-3.0 (20 °C, 10 g/L in H2O)

mp

140-142 °C

solubility

10 g/L

bulk density

200‑300 kg/m3

greener alternative category

storage temp.

2-8°C

SMILES string

[P](=O)([O-])(O[P](=O)(OCC4OC(C(C4O)O)[n+]5cc(ccc5)C(=O)N)O)OCC1OC(C(C1O)O)[n]2c3ncnc(c3nc2)N

InChI

1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)

InChI key

BAWFJGJZGIEFAR-UHFFFAOYSA-N

General description

We are committed to bringing you Greener Alternative Products that adhere to one or more of the 12 Principles of Green Chemistry. Beta-Nicotinamide adenine dinucleotide is a bio-derived redox cofactor that works together with enzymes as part of a biocatalyst system. It can be efficiently recycled in many reactions, enabling selective oxidations while reducing waste and supporting greener, more sustainable chemical processes. Click here for more information.

Application


  • Development of a Highly Selective NAD(+) -Dependent Glyceraldehyde Dehydrogenase and its Application in Minimal Cell-Free Enzyme Cascades: This research presents the development of an NAD+-dependent enzyme crucial for bioindustrial applications, demonstrating its utility in enzyme cascades for biosynthesis processes, which could enhance the efficiency of biotechnological production systems (DOI: 10.1002/css).

Analysis Note

Assay (β-NAD, enzymatically with ADH; calc. on anhydrous substance): ≥ 95 %
Assay (spectrophotometrically): ≥ 95.0 %
Identity (IR-spectrum): passes test
Appearance: White to almost white, fine powder eventuel slightly yellowish.
pH (10 g/l, water): 2.5 - 3.0
Absorption maximum λmax. (buffer pH 7.0): 259 - 261 nm
Spec. Absorptivity A1%/1cm (λmax.; 0,01 g/l; buffer pH 7.0; calc. on anhydrous substance): 255 - 270
Water (according to Karl Fischer): ≤ 7.0 %


Storage Class

13 - Non Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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