14-249-M

p38δ/SAPK4 Protein, active, 10 µg

Name: p38δ/SAPK4 Protein, active, 10 µg
Brand: MM

Active, recombinant GST fusion protein fused to full length human p38δ/SAPK4. For use in Kinase Assays.

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About This Item

UNSPSC Code:

12352202

NACRES:

NA.41

eCl@ss:

32160405

Product Name

p38δ/SAPK4 Protein, active, 10 µg, Active, recombinant GST fusion protein fused to full length human p38δ/SAPK4. For use in Kinase Assays.

biological source

human

recombinant

expressed in E. coli

mol wt

M_w 71 kDa

manufacturer/tradename

Upstate^®

technique(s)

activity assay: suitable (kinase)

Analysis Note

Routinely evaluated by phosphorylation of MBP in vitro

Biochem/physiol Actions

Protein Target: p38δ/SAPK4

Target Sub-Family: CMGC

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Product Source: expressed in E. coli

Recombinant GST fusion protein fused to full length human p38δ/SAPK4

CHK3

Other Notes

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Physical form

Affinity chromatography on glutathione Sepharose^™ beads after activation with SKK3/MEK6

Preparation Note

6 months at -20°C

Legal Information

Sepharose is a trademark of Cytiva

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

GHS07

signalword

Warning

hcodes

H317

pcodes

P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364

Hazard Classifications

Skin Sens. 1

Storage Class

10 - Combustible liquids

wgk

WGK 2

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of other SAP kinases.

M Goedert et al.

The EMBO journal, 16(12), 3563-3571 (1997-06-01)

A cDNA was cloned that encodes human stress-activated protein kinase-4 (SAPK4), a novel MAP kinase family member whose amino acid sequence is approximately 60% identical to that of the other three SAP kinases which contain a TGY motif in their

Global Trade Item Number

SKU	GTIN
14-249	04053252742460
14-249M	04053252731075

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