14-550-M

MAP Kinase 2/Erk2 Protein, active, Human, 10 µg

Name: MAP Kinase 2/Erk2 Protein, active, Human, 10 µg
Brand: MM

Active, N-terminal GST tagged, recombinant, full-length, human MAP Kinase 2/Erk2. Activated with MEK1 (Cat. # 14-429). For use in Kinase Assays.

Synonym(s):

Erk2 kinase

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About This Item

UNSPSC Code:

12352202

NACRES:

NA.41

eCl@ss:

32160405

Product Name

MAP Kinase 2/Erk2 Protein, active, Human, 10 µg, Active, N-terminal GST tagged, recombinant, full-length, human MAP Kinase 2/Erk2. Activated with MEK1 (Cat. # 14-429). For use in Kinase Assays.

biological source

human

recombinant

expressed in E. coli

mol wt

M_w 67.8 kDa

manufacturer/tradename

Upstate^®

technique(s)

activity assay: suitable (kinase)

Analysis Note

Used to phosphorylate MBP (13-104)

General description

N-terminal GST tagged, recombinant, full-length, human MAP Kinase 2/Erk2, Activated with MEK1 (14-429).

Other Notes

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Packaging

Also available in 125μg size, please inquire for pricing and availability.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

GHS07

signalword

Warning

hcodes

H317

pcodes

P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364

Hazard Classifications

Skin Sens. 1

Storage Class

10 - Combustible liquids

wgk

WGK 2

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Ras-mutant cancer cells display B-Raf binding to Ras that activates extracellular signal-regulated kinase and is inhibited by protein kinase A phosphorylation.

Yanping Li et al.

The Journal of biological chemistry, 288(38), 27646-27657 (2013-07-31)

The small G protein Ras regulates proliferation through activation of the mitogen-activated protein (MAP) kinase (ERK) cascade. The first step of Ras-dependent activation of ERK signaling is Ras binding to members of the Raf family of MAP kinase kinase kinases

Global Trade Item Number

SKU	GTIN
14-550M	04053252330902
14-550	04053252332470

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