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Merck

1.46801

Fluid Thioglycollate Medium with Neutralizers

Tween® 0.5 %, bottle capacity 500 mL, bottle filling volume 400 mL, closure type, red screw cap with septum and protector, pack of 6 bottles

Synonym(s):

FTM, FTM with 0.5% Tween®80, FTM with neutralizer, Fluid Thioglycollate Medium + 0.5% Tween® 80, Fluid Thioglycollate Medium with neutralizer, Thioglycollate Medium

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About This Item

UNSPSC Code:
41106225
NACRES:
NA.72
Bottle capacity:
500 mL
Bottle filling volume:
400 mL
Feature:
closure type red screw cap with septum and protector, ready-to-use
Agency:
EP, JP (4.06), USP

Key Documents

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material

glass bottle

agency

EP, JP (4.06), USP

sterility

sterile; autoclaved (tested for 14 days at 30 - 35°C)

form

liquid

shelf life

360 days

feature

closure type red screw cap with septum and protector, ready-to-use

composition

Agar, 0.75 g , L-Cystine, 0.5 g , Glucose x H2O, 5.5 g , NaCl, 2.5 g , Pancreatic Digest of Casein, 15 g , Polysorbate 80, 5 mL , Resazurin, 1 mg , Sodium Thioglycollate, 0.5 g , Tween®, 0.5% , Yeast Extract, 5 g

packaging

pack of 6 bottles

bottle capacity

500 mL

bottle filling volume

400 mL

pH range

6.9-7.3 (25 °C)

application(s)

food and beverages
pharmaceutical
sterility testing

storage temp.

2-25°C

suitability

nonselective for

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General description

Fluid Thioglycollate Medium (FTM) with 0.5% Tween® 80 is a complex medium. Thioglycollate and L-Cystine reduce the redox potential of the culture medium and create an anaerobic atmosphere, along with inactivating mercury and other heavy metal compounds. The presence of agar reduces a rapid diffusion of oxygen through the medium but may lead to slight turbidity in larger volumes (filled bottles). Resazurin indicates the reduction potential of the medium. An increased concentration of oxygen is indicated by a color change to pink. The polysorbate (Tween®) 80 also assists in the suspension of hydrophobic substances. It further serves to neutralize disinfectants such as quaternary ammonium compounds, iodine, and parabens.

Application

Fluid Thioglycollate Medium is used for the isolation and cultivation of fastidious anaerobic and aerobic microorganisms. It is suitable for sterility control of pharmaceutical products.

Features and Benefits

Our ready-to-use media provide the highest level of quality and testing confidence. They have been formulated and tested to meet the pharmacopeia requirements. Sterility testing media and rinse solutions are manufactured in an ISO 9001, environmentally controlled production center. Each lot undergoes a stringent quality control (QC) procedure, including pH, sterility, and growth promotion tests. Our manufacturing approach ensures the highest level of clarity for our media and rinsing fluids, thus improving accuracy and reducing the risk of incorrect interpretation and false results.

Analysis Note

The appearance of the medium is clear or almost clear and yellowish.

Other Notes

Production will take place at Millipore SAS in Molsheim, France. Deliveries will be executed in accordance with the terms and conditions of MLS RTU GmbH. A minimum order quantity is required to process the order. Once the order is placed and confirmed, Merck will ensure product delivery within a maximum timeframe of 10 to 12 weeks. The terms and conditions of Merck KGaA apply to both Millipore SAS and MLS RTU GmbH and can be accessed through the following link: Standard Terms & Conditions
This medium can be modified and/or supplemented based on the required performance criteria.

Legal Information

TWEEN is a registered trademark of Croda International PLC

Disclaimer

This item is created at the customer′s request as a customized product and will not be developed or qualified in accordance with the Merck Product Development Process.

Storage Class

12 - Non Combustible Liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

wgk

WGK 1

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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