biological source
human
mol wt
Mw 83.8 kDa
manufacturer/tradename
Upstate®
technique(s)
activity assay: suitable (phosphatase)
NCBI accession no.
Quality Level
Gene Information
human ... PPP5C(5536)
General description
Product Source: N-terminal GST-tagged, recombinant, full length, human PP5, expressed in E. coli cells.
This protein is a serine/threonine phosphatase which is a member of the protein phosphatase catalytic subunit family.
Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine
residues; many of these pathways are involved in the regulation of cell growth and differentiation. The product of
this gene has been shown to participate in signaling pathways in response to hormones or cellular stress, and elevated levels of this protein may be associated with breast cancer development. Alternative splicing results in multiple transcript variants.
Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine
residues; many of these pathways are involved in the regulation of cell growth and differentiation. The product of
this gene has been shown to participate in signaling pathways in response to hormones or cellular stress, and elevated levels of this protein may be associated with breast cancer development. Alternative splicing results in multiple transcript variants.
Analysis Note
Routinely evaluated by the release of phosphate from the substrate 6,8-difluoro-4-methylumbelliferyl phosphate (DiFMUP)
Other Notes
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Packaging
Also available in 250μg size as catalog # 14-778M and in bulk as catalog # 14-778-K.
Physical form
Purified using glutathione agarose.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1
Storage Class
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| 14-778M | 04053252738982 |
| 14-778 | 04053252507755 |
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