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Merck

1.59002

Acetonitrile solution

suitable for LC/MS, LiChrosolv®, contains 0.1% (v/v) formic acid

Synonym(s):

Acetonitrile solution, ACN, Cyanomethane, Ethyl nitrile, Methyl cyanide

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About This Item

Linear Formula:
CH3CN
CAS Number:
75-05-8
Molecular Weight:
41.05
NACRES:
NA.03
UNSPSC Code:
41116004
MDL number:
MFCD00001878
Beilstein/REAXYS Number:
4124158
technique(s):
HPLC: suitable
LC/MS: suitable
application(s):
general analytical
bp:
81.6 °C/1,013 hPa
vapor pressure:
97 hPa ( 20 °C)

Product Name

Acetonitrile with 0.1% (v/v) Formic acid, hypergrade for LC-MS LiChrosolv®

InChI key

WEVYAHXRMPXWCK-UHFFFAOYSA-N

SMILES string

CC#N

InChI

1S/C2H3N/c1-2-3/h1H3

vapor pressure

97 hPa ( 20 °C)

product line

LiChrosolv®

form

liquid

expl. lim.

3.0-17 % v()

concentration

0.095-0.105 % (v/v)

technique(s)

HPLC: suitable
LC/MS: suitable

bp

81.6 °C/1,013 hPa

mp

-45.7 °C (-50.3 °F)

transition temp

flash point 2 °C

solubility

water: soluble

density

0.782 g/mL at 25 °C

cation traces

Al: ≤0.05 ppm
Ca: ≤0.05 ppm
Fe: ≤0.05 ppm
K: ≤0.025 ppm
Mg: ≤0.05 ppm
Na: ≤0.25 ppm

application(s)

general analytical

format

mixture

storage temp.

2-30°C

Quality Level

100

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Application

LiChrosolv® hypergrade acetonitrile with 0.1% (v/v) formic acid is used as a mobile phase solvent in gradient elution of peptides by LC-MS/MS.
The product is also featured in the method development for analysis of California list of pesticides in cannabis.

Features and Benefits

  • microfiltered by 0.2 µm filter
  • the most comprehensive application range due to the largest retention time range
  • analytical reliability due to the highest possible purity and a minimum signal-to-noise ratio
  • time and cost savings due to the best possible batch consistency, thus avoiding repetitive analysis

General description

For fast chromatography and LC-MS detection, LiChrosolv® hypergrade, a family of solvents especially optimized and tested for LC-MS suitability is most suitable. LiChrosolv® hypergrade solvents meet all the requirements of modern LC-MS ionization methods (ESI/ APCI – positive and negative mode). Due to their low level of ionic background and low ion suppression, LiChrosolv® hypergrade solvents ensure high reproducibility and high ionization efficiency.

Other Notes

Explore various lab safety accessories and equipment for safe handling of solvents to increase your safety level from the first usage.

Legal Information

LICHROSOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

35.6 °F - (refers to pure substance)

flash_point_c

2 °C - (refers to pure substance)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Rasmussen M, et al.
Chemical Biology & Drug Design, 99(2), 206-221 (2022)
Rab27a co-ordinates actin-dependent transport by controlling organelle-associated motors and track assembly proteins
Alzahofi N, et al.
Nature Communications, 11(1), 1-21 (2020)

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