16-272
Anti-acetyl Lysine Antibody, clone 4G12, agarose conjugate
clone 4G12, Upstate®, from mouse
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Product Name
Anti-acetyl Lysine Antibody, clone 4G12, agarose conjugate, clone 4G12, Upstate®, from mouse
biological source
mouse
antibody form
purified antibody
antibody product type
primary antibodies
clone
4G12, monoclonal
species reactivity (predicted by homology)
all
manufacturer/tradename
Upstate®
technique(s)
immunoprecipitation (IP): suitable
shipped in
wet ice
target post-translational modification
acetylation (Lys)
Quality Level
Analysis Note
Routinely evaluated by immunoprecipitating
Application
Detect acetyl Lysine with Anti-acetyl Lysine Antibody, clone 4G12, agarose conjugate (Mouse Monoclonal Antibody), that has been shown to work in IP.
Research Category
Signaling
Epigenetics & Nuclear Function
Signaling
Epigenetics & Nuclear Function
Research Sub Category
General Post-translation Modification
Histones
General Post-translation Modification
Histones
Biochem/physiol Actions
Recognizes acetyl lysine-containing proteins including histones.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Features and Benefits
Format: Gel Immobilized
General description
varies depending upon the protein being detected
Immunogen
A mixture of chemically acetylated antigens. Clone 4G12.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Preparation Note
1 year at 4°C from date of shipment. DO NOT FREEZE.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Yan Liu et al.
Journal of proteome research, 20(5), 2596-2606 (2021-04-02)
Decreased cellular NAD+ levels are causally linked to aging and aging-associated diseases. NAD+ precursors in oxidized form such as nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR) have gained much attention and been well studied for their ability to restore NAD+
A Villagra et al.
Methods in enzymology, 573, 161-181 (2016-07-04)
Histone deacetylase assays were first developed in the 1970s, and subsequently refined in the 1990s with the cloning of HDAC enzymes. Most of these early assays, relying on traditional in vitro chemical methodologies, are still applicable today. More recently, however
Acetylation of general transcription factors by histone acetyltransferases.
Imhof, A, et al.
Current Biology, 7, 689-692 (1997)
N Munshi et al.
Molecular cell, 2(4), 457-467 (1998-11-11)
The transcriptional coactivators CBP and P/CAF are required for activation of transcription from the IFN beta enhanceosome. We show that CBP and P/CAF acetylate HMG I(Y), the essential architectural component required for enhanceosome assembly, at distinct lysine residues, causing distinct
Fei Yue et al.
Aging, 7(10), 839-853 (2015-11-06)
Autophagy controls and executes the turnover of abnormally aggregated proteins. MAP1S interacts with the autophagy marker LC3 and positively regulates autophagy flux. HDAC4 associates with the aggregation-prone mutant huntingtin protein (mHTT) that causes Huntington's disease, and colocalizes with it in
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 16-272 | 04053252403071 |
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