172103
Anaphase-Promoting Complex Inhibitor Negative Control, AAME
The Anaphase-Promoting Complex Inhibitor Negative Control, AAME, also referenced under CAS 1784-05-0, controls the biological activity of Anaphase-Promoting Complex.
Synonym(s):
Anaphase-Promoting Complex Inhibitor Negative Control, AAME, AAME hydrochloride
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About This Item
Empirical Formula (Hill Notation):
C9H18N4O3 · xHCl
CAS Number:
Molecular Weight:
230.26 (free base basis)
MDL number:
UNSPSC Code:
41106609
NACRES:
NA.77
Assay:
≥99% (TLC)
Form:
powder
Storage condition:
OK to freeze, protect from light
Quality Segment
assay
≥99% (TLC)
form
powder
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
white
solubility
water: 50 mg/mL
shipped in
ambient
storage temp.
2-8°C
SMILES string
N=C(NCCC[C@@H](C(OC)=O)NC(C)=O)N.[xHCl]
InChI
1S/C9H18N4O3.ClH/c1-6(14)13-7(8(15)16-2)4-3-5-12-9(10)11;/h7H,3-5H2,1-2H3,(H,13,14)(H4,10,11,12);1H/t7-;/m0./s1
InChI key
FIUSXBMWQFBXLZ-FJXQXJEOSA-N
General description
An acetyl-L-arginine analog of TAME that serves as a negative control. TAME is an ubiquitin ligase inhibitor that specifically blocks Anaphase-Promoting Complex (APC) activation.
Packaging
Packaged under inert gas
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Zeng, X., et al. 2010. Cancer Cell18, 382.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Regulatory Review (Z)
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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