197225
Bcl-2 Binding Peptide, Cell-Permeable, Negative Control
A cell-permeable, mutated cpm-1285 peptide analog (Leu¹⁵¹ replaced by Ala) that does not induce apoptosis and displays nearly 15-fold reduction in Bcl-2 binding.
Synonym(s):
Bcl-2 Binding Peptide, Cell-Permeable, Negative Control, Decanoyl-KN¹⁴⁰LWAAQRYGREARRMSDEFEGSFKGL¹⁶⁵-OH, cpm-1285m, cpm-1285m, Decanoyl-KN¹⁴⁰LWAAQRYGREARRMSDEFEGSFKGL¹⁶⁵-OH
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About This Item
Empirical Formula (Hill Notation):
C150H234N44O42S
Molecular Weight:
3357.80
NACRES:
NA.77
UNSPSC Code:
12352200
Assay:
≥95% (HPLC)
Form:
solid
Quality level:
Storage condition:
OK to freeze, desiccated (hygroscopic)
Quality Level
assay
≥95% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated (hygroscopic)
color
off-white
solubility
DMSO: 10 mg/mL
shipped in
ambient
storage temp.
−20°C
General description
A cell-permeable, mutated cpm-1285 peptide analog (Leu151 replaced by Ala) that does not induce apoptosis and displays nearly 15-fold reduction in Bcl-2 binding. Suitable for use as a negative control for Cat. No. 197220.
Biochem/physiol Actions
Cell permeable: yes
Reversible: no
Primary Target
A negative control for Cat. No. 197220 (Bcl-2 Binding Peptide, Cell-Permeable).
A negative control for Cat. No. 197220 (Bcl-2 Binding Peptide, Cell-Permeable).
Product does not compete with ATP.
Packaging
Packaged under inert gas
Physical form
Supplied as a trifluoroacetate salt.
Preparation Note
Following reconstitution, aliquot, flush with an inert gas, and freeze at -20°C. Stock solutions are stable for up to 2 weeks at -20°C.
Other Notes
CH₃(CH₂)₈CONH-Lys-Asn-Leu-Trp-Ala-Ala-Gln-Arg-Tyr-Gly-Arg-Glu-Ala-Arg-Arg-Met-Ser-Asp-Glu-Phe-Glu-Gly-Ser-Phe-Lys-Gly-Leu-OH
Wang, J-L., et al. 2000. Cancer Res.60, 1498.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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