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Merck

197225

Bcl-2 Binding Peptide, Cell-Permeable, Negative Control

A cell-permeable, mutated cpm-1285 peptide analog (Leu¹⁵¹ replaced by Ala) that does not induce apoptosis and displays nearly 15-fold reduction in Bcl-2 binding.

Synonym(s):

Bcl-2 Binding Peptide, Cell-Permeable, Negative Control, Decanoyl-KN¹⁴⁰LWAAQRYGREARRMSDEFEGSFKGL¹⁶⁵-OH, cpm-1285m, cpm-1285m, Decanoyl-KN¹⁴⁰LWAAQRYGREARRMSDEFEGSFKGL¹⁶⁵-OH

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About This Item

Empirical Formula (Hill Notation):
C150H234N44O42S
Molecular Weight:
3357.80
NACRES:
NA.77
UNSPSC Code:
12352200

Key Documents

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Product Name

Bcl-2 Binding Peptide, Cell-Permeable, Negative Control, A cell-permeable, mutated cpm-1285 peptide analog (Leu¹⁵¹ replaced by Ala) that does not induce apoptosis and displays nearly 15-fold reduction in Bcl-2 binding.

assay

≥95% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated (hygroscopic)

color

off-white

solubility

DMSO: 10 mg/mL

shipped in

ambient

storage temp.

−20°C

Quality Level

100

Related Categories

Biochem/physiol Actions

Cell permeable: yes
Primary Target
A negative control for Cat. No. 197220 (Bcl-2 Binding Peptide, Cell-Permeable).
Product does not compete with ATP.
Reversible: no

Disclaimer

Toxicity: Standard Handling (A)

General description

A cell-permeable, mutated cpm-1285 peptide analog (Leu151 replaced by Ala) that does not induce apoptosis and displays nearly 15-fold reduction in Bcl-2 binding. Suitable for use as a negative control for Cat. No. 197220.

Other Notes

CH₃(CH₂)₈CONH-Lys-Asn-Leu-Trp-Ala-Ala-Gln-Arg-Tyr-Gly-Arg-Glu-Ala-Arg-Arg-Met-Ser-Asp-Glu-Phe-Glu-Gly-Ser-Phe-Lys-Gly-Leu-OH
Wang, J-L., et al. 2000. Cancer Res.60, 1498.

Packaging

Packaged under inert gas

Physical form

Supplied as a trifluoroacetate salt.

Preparation Note

Following reconstitution, aliquot, flush with an inert gas, and freeze at -20°C. Stock solutions are stable for up to 2 weeks at -20°C.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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