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Peroxynitrite

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About This Item

UNSPSC Code:
41116012
NACRES:
NA.41
eCl@ss:
32160405
Form:
liquid
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form

liquid

Quality Segment

100

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

shipped in

dry ice

General description

Peroxynitrite (ONOO−) is a powerful oxidant formed by the collision of nitric oxide and superoxide.

Application

Peroxynitrite has been used to induce pericyte contraction in mouse brains. It has also been used for the preparation of positive control nitrated protein standards in immunohistochemical studies.

Biochem/physiol Actions

Peroxynitrite (ONOO−) exhibits bactericidal activity. It promotes cell death and contributes to the signal-transduction process, mitochondrial function, and apoptotic pathway. The formation of peroxynitrite has been associated with the development of various diseases including vascular diseases, ischemia-reperfusion injury, circulatory shock, inflammation, pain, and neurodegeneration.

Physical form

0.3M NaOH

Analysis Note

Routinely evaluated by treating non-stimulated A431 cells.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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pictograms

Corrosion
GHS05

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2

Storage Class

12 - Non Combustible Liquids

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