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Merck

203119

Innolink Biotin 354S

Synonym(s):

NHS-Chromogenic Biotin

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About This Item

Empirical Formula (Hill Notation):
C38H50N8O10S
Molecular Weight:
810.92
NACRES:
NA.84
UNSPSC Code:
41116133

assay

≥90% (reversed phase HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated

solubility

DMF: 50 mg/mL

shipped in

wet ice

storage temp.

2-8°C

Quality Level

Disclaimer

Toxicity: Standard Handling (A)

General description

A modified biotin conjugate in which biotin is linked to a bis-aryl hydrazone chromophore and aromatic succinimidyl ester via a long-chain PEG4 linker. The bis-aryl hydrazone chromophore allows for direct spectrophotometric quantitation of total incorporated biotin. The long-chain PEG4 linker preserves biotin/avidin affinity as well as increases solubility. The aromatic succinimidyl ester allows for higher efficiency modification of amines in aqueous buffers.

Other Notes

Steinberg-Tatman, G., et al. 2006. Bioconjug. Chem.17, 841.
Kline, M.C., et al. 2005. J. Forensic Sci.50, 1.
Kozlov, I.A., et al. 2004. Biopolymers73, 621.
Chen, Y., et al. 2004. Chem. Commun.24, 2804.
Kozlov, I.A., et al. 2004. Biopolymers73, 621.
Zhong, X.B., et al. 2003. Proc. Natl. Acad. Sci. USA100, 11559.
Hartmann, D.M., et al. 2002. Journal of Materials Research17, 473.

Preparation Note

Following reconstitution, purge with inert gas, aliquot, and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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