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203392

(+)-Blebbistatin

The inactive enantiomer of (±)-Blebbistatin.

Synonym(s):

(+)-Blebbistatin

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About This Item

Empirical Formula (Hill Notation):
C18H16N2O2
CAS Number:
1177356-70-5
Molecular Weight:
292.33
MDL number:
MFCD08460906
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
solid
Quality level:
100
Storage condition:
OK to freeze, protect from light
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Quality Level

100

assay

≥98% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, protect from light

color

yellow

solubility

methanol: 1.5 mg/mL, 100% DMSO: 100 mg/mL, 90% DMSO: 75 mg/mL

shipped in

wet ice

storage temp.

−20°C

SMILES string

N2(CC[C@]3(C2=Nc4c(cc(cc4)C)C3=O)O)c1ccccc1

InChI

1S/C18H16N2O2/c1-12-7-8-15-14(11-12)16(21)18(22)9-10-20(17(18)19-15)13-5-3-2-4-6-13/h2-8,11,22H,9-10H2,1H3/t18-/m0/s1

InChI key

LZAXPYOBKSJSEX-SFHVURJKSA-N

General description

The inactive enantiomer of (±)-Blebbistatin (Cat. No. 203390). Useful as a negative control for the active enantiomer (Cat. No. 203391).

Biochem/physiol Actions

Cell permeable: no
Primary Target
Inactive enantiomer of (±)-Blebbistatin
Product does not compete with ATP.
Reversible: no

Packaging

Packaged under inert gas

Preparation Note

Following reconstitution in methanol, aliquot and freeze (-20°C). Stock solutions in 90% DMSO or methanol are stable for up to 1 month at -20°C. Stock solutions in 100% DMSO are unstable; reconstitute just prior to use.

Other Notes

Shu, S., et al. 2005. Proc. Natl. Acad. Sci. USA102, 1472.
Jacobelli, J., et al. 2004. Nat. Immunol.5, 531.
Kovacs, M., et al. 2004. J. Biol. Chem.279, 35557.
Straight, A.F., et al. 2003. Science299, 1743.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Harmful & Carcinogenic / Teratogenic (E)

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Ying Liu et al.
Kidney diseases (Basel, Switzerland), 6(6), 422-433 (2020-12-15)
Levels of urinary microvesicles, which are increased during various kidney injuries, have diagnostic potential for renal diseases. However, the significance of urinary microvesicles as a renal disease indicator is dampened by the difficulty to ascertain their cell source. The aim