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Merck

204881

Complement C3a Peptide

≥95% (SDS-PAGE), liquid, human

Synonym(s):

C3a Protein

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.77

Product Name

Complement C3a, Human, Complement C3a, Human, is a native, single chain C3a complement component. It has many biological activities, such as smooth muscle contraction, platelet activation, & immunoregulatory reactions.

assay

≥95% (SDS-PAGE)

form

liquid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

impurities

≤10% C3adesArg

shipped in

wet ice

storage temp.

−70°C

Quality Level

100

Disclaimer

Toxicity: Standard Handling (A)

General description

Native, human C3a complement component. Single chain, 77 amino acid peptide. Activation of either complement pathway can result in formation of C3-cleaving enzyme (C3 convertases) on target surfaces. The C3 convertase enzymes of either complement activation pathway will cleave the C3 α-chain at peptide bond 77, resulting in the production and release of the C3a peptide. C3a, one of the three complement-derived anaphylatoxins, expresses a wide variety of biological activities, which include smooth muscle contraction, platelet and neutrophil activation and aggregation, skin wheal and flare, and immunoregulatory reactions.

Other Notes

Hugli, T.E. 1989. Curr. Top. Micro. Immunol. 153, 181.
Hugli, T.E. 1986. Complement 3, 111.

Packaging

Please refer to vial label for lot-specific concentration.

Physical form

In PBS, pH 7.2, sterile-filtered through a 0.22 µm filter.

Preparation Note

Following initial thaw, aliquot and freeze (-70°C).
Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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