208735
Calmodulin Inhibitory Peptide
The Calmodulin Inhibitory Peptide controls the biological activity of Calmodulin. This small molecule/inhibitor is primarily used for Cell Signaling applications.
Synonym(s):
Calmodulin Inhibitory Peptide, MLCK Peptide, MLCKP
Sign In to View Organizational & Contract Pricing.
Select a Size
About This Item
Empirical Formula (Hill Notation):
C91H156N36O20
Molecular Weight:
2074.44
NACRES:
NA.77
UNSPSC Code:
12352202
Assay:
≥95% (HPLC)
Form:
lyophilized
Quality level:
Storage condition:
OK to freeze, desiccated (hygroscopic)
assay
≥95% (HPLC)
form
lyophilized
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated (hygroscopic)
solubility
water: 50 mg/mL
shipped in
ambient
storage temp.
−20°C
Quality Level
Related Categories
General description
A 17-residue peptide based on the calmodulin-binding domain of myosin light chain kinase (MLCK). Binds to calmodulin with high affinity (Kd = 6 pM). Inhibits calmodulin activation of MLCK-catalyzed phosphorylation of smooth muscle regulatory light chain(MLC).
Biochem/physiol Actions
Cell permeable: no
Kd = 6 pM in binding to calmodulin
Primary Target
Calmodulin
Calmodulin
Product does not compete with ATP.
Reversible: no
Physical form
Supplied as a trifluoroacetate salt.
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Ac-Arg-Arg-Lys-Trp-Gln-Lys-Thr-Gly-His-Ala-Val-Arg-Ala-Ile-Gly-Arg-Leu-NH₂
Torok,K., et al. 1998. Biochemistry 37, 6188.
Török, K., and Trentham, D.R. 1994. Biochemistry33, 12807.
Török, K., and Trentham, D.R. 1994. Biochemistry33, 12807.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service