210150
Cantharidic Acid
A potent inhibitor of protein phosphatase 2A (IC50 = 50 nM).
Synonym(s):
Cantharidic Acid, 5ʹ-3ʹ2,3-Dicarboxy-2,3-dimethyl-1,4-epoxycyclohexane, exo-1,6-Dicarboxy- endo-1,6-dimethyl-7-oxabicylco[2,2,1]heptane
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About This Item
Product Name
Cantharidic Acid, A potent inhibitor of protein phosphatase 2A (IC50 = 50 nM).
SMILES string
O1[C@@H]2[C@@]([C@@]([C@H]1CC2)(C)C(=O)O)(C)C(=O)O
InChI
1S/C10H14O5/c1-9(7(11)12)5-3-4-6(15-5)10(9,2)8(13)14/h5-6H,3-4H2,1-2H3,(H,11,12)(H,13,14)/t5-,6+,9-,10+
InChI key
NMTNUQBORQILRK-YUMGAWCOSA-N
assay
>95% (TLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
color
white
solubility
warm ethanol: 10 mg/mL
DMSO: 25 mg/mL
shipped in
ambient
storage temp.
10-30°C
Quality Level
Related Categories
Other Notes
Li, Y.-M., and Casida, J.E. 1992. Proc. Natl. Acad. Sci. USA89, 11867.
Graziano, M.J., et al. 1988. Mol. Pharmacol.33, 706.
Preparation Note
Legal Information
Biochem/physiol Actions
PP2A
Disclaimer
General description
Storage Class
11 - Combustible Solids
wgk
WGK 3
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