218735
Caspase Inhibitor II
The Caspase Inhibitor II, also referenced under CAS 147837-52-3, controls the biological activity of Caspase. This small molecule/inhibitor is primarily used for Cancer applications.
Synonym(s):
Caspase Inhibitor II, Ac-VAD-CHO
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About This Item
Empirical Formula (Hill Notation):
C14H23N3O6
CAS Number:
Molecular Weight:
329.35
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Quality Level
assay
≥95% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
color
white
solubility
DMSO: 150 mg/mL
shipped in
ambient
storage temp.
−20°C
SMILES string
N([C@@H](CC(=O)O)C=O)C(=O)[C@@H](NC(=O)[C@@H](NC(=O)C)C(C)C)C
InChI
1S/C14H23N3O6/c1-7(2)12(16-9(4)19)14(23)15-8(3)13(22)17-10(6-18)5-11(20)21/h6-8,10,12H,5H2,1-4H3,(H,15,23)(H,16,19)(H,17,22)(H,20,21)/t8-,10-,12-/m0/s1
InChI key
BGFYQRSQECIBIB-PEXQALLHSA-N
General description
A potent and reversible inhibitor of caspases.
A potent and reversible pan-caspase inhibitor.
Biochem/physiol Actions
Product does not compete with ATP.
Reversible: yes
Cell permeable: no
Primary Target
pan-caspase
pan-caspase
Preparation Note
Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Ac-Val-Ala-Asp-CHO
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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