218740
Caspase-2 Substrate I, Fluorogenic
A fluorogenic substrate for the detection of caspase-2 (ICH-1).
Synonym(s):
Caspase-2 Substrate I, Fluorogenic, Z-VDVAD-AFC
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About This Item
Empirical Formula (Hill Notation):
C39H45F3N6O13
Molecular Weight:
862.80
UNSPSC Code:
12352200
Quality Level
assay
≥95% (HPLC)
form
lyophilized
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated, protect from light
solubility
DMSO: 5 mg/mL
fluorescence
λex ~400 nm, λem ~505 nm
shipped in
ambient
storage temp.
−20°C
General description
A fluorogenic substrate for detection of caspase-2 (ICH-1). Reaction can be monitored visually or quantitatively by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore (excitation max: ~400 nm; emission max: ~505 nm).
This product has been discontinued.
A fluorogenic substrate for the detection of caspase-2 (ICH-1). Reaction can be monitored visually or quantitatively by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore.
A fluorogenic substrate for the detection of caspase-2 (ICH-1). Reaction can be monitored visually or quantitatively by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore.
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Ito, A., et al. 1999. Biochim. Biophys. Acta1452, 263.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Talanian, R.V., et al. 1997. J. Biol. Chem. 272, 9677.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Talanian, R.V., et al. 1997. J. Biol. Chem. 272, 9677.
Z-Val-Asp-Val-Ala-Asp-AFC
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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