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Merck

218763

Caspase-6 Substrate III, Fluorogenic

A fluorogenic substrate for caspase-6 (Mch2).

Synonym(s):

Caspase-6 Substrate III, Fluorogenic, Z-VEID-AFC

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About This Item

Empirical Formula (Hill Notation):
C38H44F3N5O12
CAS Number:
Molecular Weight:
819.78
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥95% (HPLC)
Form:
lyophilized
Quality level:
Storage condition:
OK to freeze, desiccated, protect from light
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Quality Level

assay

≥95% (HPLC)

form

lyophilized

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, desiccated, protect from light

solubility

DMSO: 5 mg/mL

fluorescence

λex ~400 nm, λem ~505 nm

shipped in

ambient

storage temp.

−20°C

SMILES string

FC(F)(F)C1=CC(=O)Oc2c1ccc(c2)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)OCc3ccccc3)C(C)C)CCC(=O)O)[C@H](CC)C)CC(=O)O

InChI key

OEVAAZFKVRJQQH-UXAYAQJLSA-N

General description

A fluorogenic substrate for caspase-6 (Mch2). Reaction can be monitored visually or quantitatively by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore (excitation maximum: ~400 nm; emission maximum: ~505 nm).

Biochem/physiol Actions

Cell permeable: no
Primary Target
A fluorogenic substrate for caspase-6 (Mch2
Product does not compete with ATP.
Reversible: no

Other Notes

Z-Val-Glu-Ile-Asp-AFC

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)


hcodes

Hazard Classifications

Aquatic Chronic 4

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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