Caspase-2, Human, Recombinant, E. coli

Name: Caspase-2, Human, Recombinant, <i>E. coli</i>
Brand: MM

Caspase-2, Human, Recombinant, E. coli is expressed as a single polypeptide chain that undergoes spontaneous autoprocessing to yield the native active enzyme.

Synonym(s):

ICH-1, Nedd-2

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About This Item

UNSPSC Code:

12352202

Product Name

Caspase-2, Human, Recombinant, E. coli, Caspase-2, Human, Recombinant, E. coli is expressed as a single polypeptide chain that undergoes spontaneous autoprocessing to yield the native active enzyme.

recombinant

expressed in E. coli

assay

≥90% (SDS-PAGE)

form

lyophilized solid

specific activity

≥1500 units/mg protein

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze

solubility

PBS: 0.1-1 units/μL

shipped in

wet ice

storage temp.

−70°C

Quality Level

100

Disclaimer

Toxicity: Standard Handling (A)

General description

Recombinant, human caspase-2 expressed in E. coli as a single polypeptide chain. Subsequently undergoes spontaneous auto-processing to yield the native active enzyme. Useful for the study of enzyme regulation, cleavage of target substrates, and inhibitor screening. Cleavage sites are located at Asp³¹⁶, Asp³³⁰, and possibly Asp¹⁵². MW: 12000 and 19000.

Other Notes

One unit is defined as the amount of enzyme that will cleave 1.0 nmol of Ac-VDVAD-pNA (Cat. No. 218820) per h at 37°C, pH 7.2.

Talanian, R.V., et al. 1997. J. Biol. Chem.272, 9677.
Wang, L., et al. 1994. Cell78, 739.

Preparation Note

Following reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 6 months at -70°C.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Caspase-2, Human, Recombinant, E. coli