219011
Caspase Inhibitor VI
InSolution, ≥95%
Synonym(s):
InSolution Caspase Inhibitor VI
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About This Item
Empirical Formula (Hill Notation):
C21H28FN3O7
Molecular Weight:
453.46
NACRES:
NA.54
UNSPSC Code:
12352200
Assay:
≥95% (TLC)
Form:
liquid
Quality level:
Storage condition:
OK to freeze, desiccated, protect from light
Quality Level
assay
≥95% (TLC)
form
liquid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated, protect from light
shipped in
wet ice
storage temp.
−20°C
General description
A cell-permeable, irreversible, and general caspase inhibitor. Also reported to inhibit Peptide: N-glycanase (PNGase) in vitro and in vivo. Useful for studies involving recombinant, isolated, and purified caspase enzymes. Unlike Caspase Inhibitor I (Cat. No. 627610), this inhibitor does not require pretreatment with esterase for in vitro studies.
Biochem/physiol Actions
Reversible: no
Primary Target
general caspase inhibitor
general caspase inhibitor
Product does not compete with ATP.
Cell permeable: yes
Packaging
Packaged under inert gas
Physical form
A 10 mM (1 mg/221 µl) solution of Caspase Inhibitor VI (Cat. No. 219007) in DMSO.
Preparation Note
Following initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 3 months at -20°C.
Other Notes
Misaghi, S., et al. 2004. Chem. Biol.11, 1677.
Z-Val-Ala-Asp-CH₂F*
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Irritant (B)
Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
188.6 °F
flash_point_c
87 °C
Certificates of Analysis (COA)
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