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Merck

219369

Carcinoembryonic Antigen, Human Colon Adenocarcinoma Cell Line

Carcinoembryonic Antigen, Human Colon Adenocarcinoma Cell Line, is a native CEA from human colon adenocarcinoma cells.

Synonym(s):

CEA

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About This Item

NACRES:
NA.42
UNSPSC Code:
12352202

Key Documents

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Product Name

Carcinoembryonic Antigen, Human Colon Adenocarcinoma Cell Line, Carcinoembryonic Antigen, Human Colon Adenocarcinoma Cell Line, is a native CEA from human colon adenocarcinoma cells.

form

lyophilized

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

solubility

aqueous buffer: soluble

shipped in

ambient

storage temp.

−20°C

Quality Level

100

Analysis Note

single diffuse band by SDS-PAGE

Disclaimer

Toxicity: Standard Handling (A)

General description

Native CEA from human colon adenocarcinoma cells. Found in tumors in adults. Widely used cancer marker found on many adult tumors. For more than a decade, purified CEA has been the most widely used general marker in determining and monitoring the status of malignant disease. This preparation is derived from an established adenocarcinoma cell line.

Other Notes

Nomoto, K., et al. 1998. Jpn. J. Cancer Res. 89, 1257.
Jacobs, E.L., and Haskell, C.M. 1991. Curr. Probl. Cancer15, 299.
Robertson, J.F., et al. 1991. Br. J. Cancer64, 757.

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Lincidio Perez et al.
Biotechnology and applied biochemistry, 43(Pt 1), 39-48 (2005-08-17)
In the present paper we report the development of a bivalent scFv (single-chain Fv) antibody fragment, starting from a mouse mAb (monoclonal antibody) specific for CEA (carcinoembryonic antigen) that has received approval for in vivo radioimmunodiagnosis in humans. The diabody
Ana Alvarez-Cienfuegos et al.
Scientific reports, 6, 28643-28643 (2016-06-28)
Here, we describe a new strategy that allows the rapid and efficient engineering of mono and multispecific trivalent antibodies. By fusing single-domain antibodies from camelid heavy-chain-only immunoglobulins (VHHs) to the N-terminus of a human collagen XVIII trimerization domain (TIE(XVIII)) we

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