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230914

Chymotrypsin Substrate II

≥98% (HPLC), fluorogenic chymotrypsin substrate, lyophilized solid

Synonym(s):

Chymotrypsin Substrate II, Fluorogenic, Suc-AAPF-AMC

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About This Item

Empirical Formula (Hill Notation):
C34H39N5O9
CAS Number:
88467-45-2
Molecular Weight:
661.70
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
MFCD00080246

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Product Name

Chymotrypsin Substrate II, Fluorogenic, Sensitive fluorogenic substrate for the quantitative determination of chymotrypsin activity.

SMILES string

N1([C@@H](CCC1)C(=O)NC(=O)[C@@H](Nc3cc4c(cc3)C(=CC(=O)O4)C)Cc2ccccc2)C(=O)[C@@H](NC(=O)[C@@H](NC(=O)CCC(=O)O)C)C

InChI

1S/C34H39N5O9/c1-19-16-30(43)48-27-18-23(11-12-24(19)27)37-25(17-22-8-5-4-6-9-22)32(45)38-33(46)26-10-7-15-39(26)34(47)21(3)36-31(44)20(2)35-28(40)13-14-29(41)42/h4-6,8-9,11-12,16,18,20-21,25-26,37H,7,10,13-15,17H2,1-3H3,(H,35,40)(H,36,44)(H,41,42)(H,38,45,46)/t20-,21-,25-,26-/m0/s1

InChI key

IGKPQFYMWKQDQS-KCXKOMAXSA-N

assay

≥98% (HPLC)

form

lyophilized solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated
protect from light

color

white

solubility

DMSO: soluble
acetonitrile: water (1:1): soluble

fluorescence

λex ~380 nm
λem ~460 nm

shipped in

ambient

storage temp.

−20°C

Quality Level

100

Related Categories

Biochem/physiol Actions

Cell permeable: no
Primary Target
Chymotrypsin
Product does not compete with ATP.
Reversible: no

Disclaimer

Toxicity: Standard Handling (A)

General description

Sensitive fluorogenic substrate for the quantitative determination of chymotrypsin activity (excitation maximum: ~380 nm; emission maximum: ~460 nm).

Other Notes

Irvine, G.B., et al. 1990. Anal. Biochem.185, 304.
Graf, L., et al. 1987. Biochemistry26, 2616.
Oshima, G. 1984. J. Biochem.95, 1131.
Oshima, G. 1983. J. Biochem.94, 1615.
Suc-Ala-Ala-Pro-Phe-AMC

Preparation Note

Following reconstitution aliquot and freeze (-20°C). Avoid freeze/thaw cycles of solutions. Stock solutions are stable for up to 3 months at -20°C.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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