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230914

Chymotrypsin Substrate II

≥98% (HPLC), fluorogenic chymotrypsin substrate, lyophilized solid

Synonym(s):

Chymotrypsin Substrate II, Fluorogenic, Suc-AAPF-AMC

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About This Item

Empirical Formula (Hill Notation):
C34H39N5O9
CAS Number:
88467-45-2
Molecular Weight:
661.70
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
MFCD00080246

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Product Name

Chymotrypsin Substrate II, Fluorogenic, Sensitive fluorogenic substrate for the quantitative determination of chymotrypsin activity.

SMILES string

N1([C@@H](CCC1)C(=O)NC(=O)[C@@H](Nc3cc4c(cc3)C(=CC(=O)O4)C)Cc2ccccc2)C(=O)[C@@H](NC(=O)[C@@H](NC(=O)CCC(=O)O)C)C

InChI

1S/C34H39N5O9/c1-19-16-30(43)48-27-18-23(11-12-24(19)27)37-25(17-22-8-5-4-6-9-22)32(45)38-33(46)26-10-7-15-39(26)34(47)21(3)36-31(44)20(2)35-28(40)13-14-29(41)42/h4-6,8-9,11-12,16,18,20-21,25-26,37H,7,10,13-15,17H2,1-3H3,(H,35,40)(H,36,44)(H,41,42)(H,38,45,46)/t20-,21-,25-,26-/m0/s1

InChI key

IGKPQFYMWKQDQS-KCXKOMAXSA-N

assay

≥98% (HPLC)

form

lyophilized solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, desiccated, protect from light

color

white

solubility

DMSO: soluble, acetonitrile: water (1:1): soluble

fluorescence

λex ~380 nm, λem ~460 nm

shipped in

ambient

storage temp.

−20°C

Quality Level

100

Related Categories

General description

Sensitive fluorogenic substrate for the quantitative determination of chymotrypsin activity (excitation maximum: ~380 nm; emission maximum: ~460 nm).

Biochem/physiol Actions

Cell permeable: no
Primary Target
Chymotrypsin
Product does not compete with ATP.
Reversible: no

Preparation Note

Following reconstitution aliquot and freeze (-20°C). Avoid freeze/thaw cycles of solutions. Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Irvine, G.B., et al. 1990. Anal. Biochem.185, 304.
Graf, L., et al. 1987. Biochemistry26, 2616.
Oshima, G. 1984. J. Biochem.95, 1131.
Oshima, G. 1983. J. Biochem.94, 1615.
Suc-Ala-Ala-Pro-Phe-AMC

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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