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Merck

234167

Anti-Collagen Type I Rabbit pAb

liquid, Calbiochem®

Synonym(s):

Anti-Collagen I Antibody

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Clone:
polyclonal
Species reactivity:
mouse, human, rat
Application:
—
Citations:
48

Key Documents

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biological source

rabbit

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

form

liquid

does not contain

preservative

species reactivity

mouse, human, rat

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, avoid repeated freeze/thaw cycles

dilution

(Frozen Sections (1:30-1:60)
Immunoblotting (1:200-1:500)
Immunofluorescence (1:20-1:40)
Immunoprecipitation (1:20-1:60))

isotype

IgG

shipped in

wet ice

storage temp.

−70°C

target post-translational modification

unmodified

Quality Level

100

General description

Rabbit polyclonal antibody supplied as undiluted serum. Recognizes the ~115 kDa (doublet) type I collagen protein.
Recognizes type I collagen. Exhibits slight cross-reactivity with type III collagen.
This Anti-Collagen Type I Rabbit pAb is validated for use in Frozen Sections, Immunoblotting, Immunofluorescence, Immunoprecipitation for the detection of Collagen Type I.

Immunogen

Fetal Mouse Skin
purified, fetal mouse skin collagen type I

Application

Frozen Sections (1:30-1:60, see comments)

Immunoblotting (1:200-1:500)

Immunofluorescence (1:20-1:40)

Immunoprecipitation (1:20-1:60)

Physical form

Undiluted serum.

Preparation Note

Following initial thaw, aliquot and freeze (-70°C).

Other Notes

Romanos, G.E., et al. 1992. J. Periodont. Res. 27, 101.
Zimmermann, B., et al. 1992. Eur. Arch. Biol. 103, 93.
Schröter-Kermani, C., et al. 1991. Matrix 11, 428.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Mei Li et al.
International journal of molecular medicine, 38(2), 513-520 (2016-06-18)
Hepatitis B virus (HBV)-associated glomerulo-nephritis is the most common extra-hepatic disorder occurring with hepatitis B virus infection. In the present study, we hypothesized that HBV X protein (HBx) may play a critical role in renal interstitial fibrosis, as HBx has been shown to induce epithelial-mesenchymal transition (EMT)
Kristin V T Engebretsen et al.
Journal of applied physiology (Bethesda, Md. : 1985), 114(8), 988-997 (2013-02-16)
On the basis of the role of small, leucine-rich proteoglycans (SLRPs) in fibrogenesis and inflammation, we hypothesized that they could be involved in cardiac remodeling and reverse remodeling as occurs during aortic stenosis and after aortic valve replacement. Thus, in
Kun Zhang et al.
Theranostics, 9(25), 7566-7582 (2019-11-07)
Liver fibrosis leading to cirrhosis is one of the major health burdens worldwide with currently limited therapeutic options available. Long noncoding RNAs (lncRNAs) play important roles in various biological and pathological processes in a cell- or tissue-specific manner. However, there
Yusuke Kubo et al.
International journal of molecular sciences, 21(3) (2020-02-12)
Tenocytes are mechanosensitive cells intimately adapting their expression profile and hence, their phenotype to their respective mechanomilieu. The immunolocalization and expression intensity of tenogenic, anabolic and catabolic markers in tenocytes in response to in vitro mechanical loading have not been
Liangxiang Xiao et al.
Experimental and therapeutic medicine, 18(3), 2029-2036 (2019-08-15)
Diabetic nephropathy (DN) is the leading cause of end-stage renal disease worldwide with high morbidity and mortality. Glomerular mesangial cell (MC) proliferation, inflammatory cell infiltration and extracellular matrix (ECM) accumulation are the main pathological characteristics of DN. A previous study
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