234599
Conduritol B Epoxide
≥98% (HPLC), solid, Glucocerebrosidase inhibitor, Calbiochem®
Synonym(s):
Conduritol B Epoxide, CBE, 1,2-Anhydro-myo-inositol
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About This Item
Empirical Formula (Hill Notation):
C6H10O5
CAS Number:
Molecular Weight:
162.14
MDL number:
UNSPSC Code:
12352119
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
solid
Storage condition:
OK to freeze, desiccated
Product Name
Conduritol B Epoxide, Conduritol B Epoxide, CAS 6090-95-5, is an irreversible Inhibitor of glucocerebrosidase in neurons. Also inhibits α-glucosidase activity in a variety of species.
Quality Segment
assay
≥98% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated
color
white
solubility
DMSO: soluble, water: soluble
shipped in
ambient
storage temp.
−20°C
SMILES string
O1[C@@H]2[C@H]1[C@@H]([C@H]([C@@H]([C@H]2O)O)O)O
InChI
1S/C6H10O5/c7-1-2(8)4(10)6-5(11-6)3(1)9/h1-10H/t1-,2-,3+,4+,5-,6+/m0/s1
InChI key
ZHMWOVGZCINIHW-FTYOSCRSSA-N
General description
Inhibits α-glucosidase activity in mammals, snails, sweet almonds and yeast. An irreversible, potent, and specific inhibitor of glucocerebrosidase in cultured neurons. Has also been shown to inhibit α-glucosidase from yeast, and rabbit intestinal sucrase-isomaltase complex.
Biochem/physiol Actions
Cell permeable: no
Primary Target
α-glucosidase
α-glucosidase
Product does not compete with ATP.
Reversible: no
Preparation Note
Unstable in solution; reconstitute just prior to use.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Harmful (C)
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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