252926
N-Acetylneuraminic Acid, 2,3-Dehydro-2-deoxy-, Sodium Salt
Inhibitor of bacterial, viral, and mammalian neuraminidases. Ki = 4 µM for influenza virus neuraminidase. Believed to act by binding to the catalytic site of neuraminidase as a transition state analog.
Synonym(s):
N-Acetylneuraminic Acid, 2,3-Dehydro-2-deoxy-, Sodium Salt
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About This Item
Empirical Formula (Hill Notation):
C11H16NNaO8
Molecular Weight:
313.24
NACRES:
NA.79
UNSPSC Code:
12352201
Quality Segment
assay
≥95% (TLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated (hygroscopic)
color
off-white to pale yellow
solubility
water: 1 mM
shipped in
ambient
storage temp.
−20°C
General description
A ganglioside neuraminidase inhibitor that is believed to act by binding to the catalytic site of neuraminidase. Reported to inhibit influenza virus neuraminidase (Ki = 4 µM). Also inhibits bacterial, viral, and mammalian neuraminidases.
Inhibitor of bacterial, viral, and mammalian neuraminidases. Ki = 4 µM for influenza virus neuraminidase. Believed to act by binding to the catalytic site of neuraminidase as a transition state analog.
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Other Notes
Kopitz, J., et al. 1997. Eur. J. Cell. Biol.73, 1.
Holzer, C.T., et al. 1993. Glycoconj. J.10, 40.
Chong, A.K., et al. 1991. Biochem. Int.24, 165.
Holzer, C.T., et al. 1993. Glycoconj. J.10, 40.
Chong, A.K., et al. 1991. Biochem. Int.24, 165.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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