260575
1-Deoxymannojirimycin, Hydrochloride
A specific α-mannosidase I inhibitor that blocks conversion of high mannose to complex oligosaccharides.
Synonym(s):
1-Deoxymannojirimycin, Hydrochloride, DMJ, 1,5-Dideoxy-1,5-imino-D-mannitol, HCl
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About This Item
Empirical Formula (Hill Notation):
C6H13NO4 · xHCl
CAS Number:
Molecular Weight:
163.17 (free base basis)
UNSPSC Code:
12352200
Assay:
≥98% (TLC)
Form:
crystalline solid
Storage condition:
OK to freeze, desiccated (hygroscopic)
Quality Segment
assay
≥98% (TLC)
form
crystalline solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated (hygroscopic)
color
white
solubility
ethanol: 1 mg/mL, water: 1 mg/mL
shipped in
ambient
storage temp.
−20°C
InChI
1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4-,5-,6-/m1/s1
InChI key
LXBIFEVIBLOUGU-KVTDHHQDSA-N
General description
Special α-mannosidase I inhibitor that blocks conversion of high mannose to complex oligosaccharides.
A specific α-mannosidase I inhibitor that blocks conversion of high mannose to complex oligosaccharides.
Biochem/physiol Actions
Cell permeable: no
Primary Target
α-mannosidase-I
α-mannosidase-I
Product does not compete with ATP.
Reversible: no
Packaging
Packaged under inert gas
Preparation Note
Following reconstitution, aliquot and freeze (-20°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 6 months at -20°C.
Other Notes
Suzuki, S.S., and Piette, L.H. 1993. J. Cell. Biochem.51, 181.
Fuhrmann, U., et al. 1984. Nature307, 755.
Fuhrmann, U., et al. 1984. Nature307, 755.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Harmful (C)
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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