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Merck

263301

Dermatan Sulfate, Porcine Intestinal Mucosa - CAS 54328-33-5 - Calbiochem

Mucopolysaccharide containing iduronic acid. Shown to inhibit adenylate kinase from rat hepatic membranes and acts as a potent mediator of fibroblast growth factor-2 responsiveness.

Synonym(s):

Dermatan Sulfate, Porcine Intestinal Mucosa - CAS 54328-33-5 - Calbiochem, Iduronic Acid-β-1,4-N-acetyl-D-galactosamine, Chrondroitin Sulfate B

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About This Item

CAS Number:
54328-33-5
UNSPSC Code:
12352201
MDL number:
MFCD00151683

Key Documents

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Product Name

Dermatan Sulfate, Porcine Intestinal Mucosa - CAS 54328-33-5 - Calbiochem, Mucopolysaccharide containing iduronic acid. Shown to inhibit adenylate kinase from rat hepatic membranes and acts as a potent mediator of fibroblast growth factor-2 responsiveness.

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white

solubility

water: 5 mg/mL

shipped in

ambient

storage temp.

2-8°C

Quality Level

100

Disclaimer

Toxicity: Standard Handling (A)

General description

Iduronic acid-containing mucopolysaccharide abundant in skin, arterial walls, and heart valves. Shown to inhibit both Gpp(NH)p- and FSK-stimulated adenylate cyclase activity in rat hepatic membrane preparations and act as an active mediator of fibroblast growth factor-2 responsiveness in wound healing via FGF-2 affinity interaction (KD 2.48 µM). M.W. 30,000 (avg.).
M.W. 30,000 (avg.).

Other Notes

Dittmann, J., et al. 1998. Life Sci. 63, 2199.
Penc, S.F., et al. 1998. J. Biol. Chem. 273, 28116.

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months ant -20°C.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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