311204
Nᴳ,NG′-Dimethyl-L-arginine dihydrochloride
≥97% (HPLC), solid, nitric oxide synthesis inhibitor, Calbiochem®
Synonym(s):
NG,NG′-Dimethyl-L-arginine, Dihydrochloride, SDMA, 2HCl
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About This Item
Empirical Formula (Hill Notation):
C8H18N4O2 · 2HCl
Molecular Weight:
275.18
UNSPSC Code:
12352209
NACRES:
NA.77
Assay:
≥97% (HPLC)
Form:
solid
Storage condition:
OK to freeze, desiccated (hygroscopic)
Product Name
NG,NG′-Dimethyl-L-arginine, Dihydrochloride, Cell permeable. Endogenous inhibitor of nitric oxide synthesis in vitro and in vivo. Does not exhibit any significant inhibitory effect on NOS activity.
Quality Segment
assay
≥97% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated (hygroscopic)
color
white to light yellow
solubility
water: 50 mg/mL
shipped in
wet ice
storage temp.
2-8°C
General description
A cell-permeable endogenous inhibitor of nitric oxide synthesis in vitro and in vivo. Does not exhibit any significant inhibitory effect on NOS activity.
Cell permeable. Endogenous inhibitor of nitric oxide synthesis in vitro and in vivo. Does not exhibit any significant inhibitory effect on NOS activity.
Biochem/physiol Actions
Cell permeable: yes
Primary Target
NOS in vitro
NOS in vitro
Product does not compete with ATP.
Reversible: no
Other Notes
Nam, S.W., et al. 1998. Arch. Pharm. Res. 21, 128.
Closs, E.I., et al. 1997. Nitric Oxide 1, 65.
Kotani, K., et al. 1992. J. Neurochem.58, 1127.
Closs, E.I., et al. 1997. Nitric Oxide 1, 65.
Kotani, K., et al. 1992. J. Neurochem.58, 1127.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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