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324483

Ebselen

Name: Ebselen
Brand: MM

Synonym(s):

Ebselen, 2-Phenyl-1,2-benzisoselenazol-3(2H)-one

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About This Item

Empirical Formula (Hill Notation):

C₁₃H₉NOSe

CAS Number:

60940-34-3

Molecular Weight:

274.18

UNSPSC Code:

12352200

NACRES:

NA.32

MDL number:

MFCD00210937

eCl@ss:

32160703

Form:

lyophilized solid

Storage condition:

OK to freeze

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Properties

form

lyophilized solid

storage condition

OK to freeze

solubility

soluble (DMSO (5 mg/ml) or Ethanol)

storage temp.

−20°C

SMILES string

O=C1N([Se]c2ccccc12)c3ccccc3

InChI

1S/C13H9NOSe/c15-13-11-8-4-5-9-12(11)16-14(13)10-6-2-1-3-7-10/h1-9H

InChI key

DYEFUKCXAQOFHX-UHFFFAOYSA-N

Description

General description

Non-selective, cell-permeable, inhibitor of the cyclooxygenase activity of prostaglandin H synthase 1 and 2. An excellent scavenger of peroxynitrite. Glutathione peroxidase mimetic. Inhibits radiation-induced apoptosis in thymocytes by scavenging peroxides. A neuroprotective agent against acute focal ischemic injury.

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