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Merck

341597

FGF-II, Mouse, Recombinant, E. coli

Synonym(s):

mFGF-II, Fibroblast Growth Factor-II

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About This Item

UNSPSC Code:
12352202
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assay

≥95% (SDS-PAGE)

form

lyophilized solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

impurities

≤0.1 ng/μg Endotoxins (ng/μg FGF-2)

color

white

shipped in

wet ice

storage temp.

−20°C

Quality Level

Biochem/physiol Actions

ED₅₀: ≤0.5 ng/ml as determined by the dose-dependent proliferation of BALB/3T3 cells.

Disclaimer

Toxicity: Standard Handling (A)

General description

Full-length, recombinant, mouse basic fibroblast growth factor expressed in E. coli. A multi-functional factor with chemotactic activity for numerous cell types. It plays a role in the proliferation of neuronal precursors and in neuronal differentiation. A potent angiogenic factor both in vivo and in vitro. Activates phospholipase D in endothelial cells. Mouse FGFII shares 95% identity with human FGFII. Useful for studies of cell activation and signaling.

Other Notes

Coulier, F. et al. 1997. J. Mol Evol.44, 43.
Claus, P. et al., 2003. J. Biol. Chem.278, 749.

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. Avoid freeze/thaw cycles of solutions.
Reconstitute to 100 µg/ml with sterile H₂O.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10-13 - German Storage Class 10 to 13


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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