341631
Bovine Fibronectin
from bovine plasma, liquid, suitable for cell culture
Synonym(s):
Fibronectin, Bovine Plasma
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About This Item
Form:
solution
Product Name
Fibronectin, Bovine Plasma, solution, Extracellular matrix (ECM) glycoprotein, Suitable for cell adhesion, growth, migration, and differentiation.
Quality Segment
description
Merck USA index - 14, 4075
form
solution
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, avoid repeated freeze/thaw cycles
shipped in
dry ice
storage temp.
−20°C
General description
Fibronectin is an extracellular matrix (ECM) glycoprotein. It is expressed in various cell types. Fibronectin exists as a dimer and is made up of identical subunits which are linked covalently via a disulfide bond at their C-termini.
Application
Fibronectin, Bovine Plasma has been used as an extracellular matrix (ECM) substrate to coat dishes or polyacrylamide hydrogels for adhering:
- human melanoma cancer cells
- human breast epithelial cells
- mouse embryonic fibroblasts
Biochem/physiol Actions
Fibronectin plays a role in cell adhesion, growth, migration, and differentiation. It binds to several molecules such as integrins, heparin, fibrin, and collagen.
Packaging
Please refer to vial label for lot-specific concentration.
Physical form
In 150 mM NaCl, 20 mM sodium phosphate buffer, pH 7.3.
Preparation Note
Following initial thaw, aliquot and freeze (-20°C).
Analysis Note
single band by SDS-PAGE
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Storage Class
10 - Combustible liquids
wgk
WGK 2
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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