344597
FTY720
Synonym(s):
2-Amino-2-(2-(4-octylphenyl)ethyl)propane-1,3-diol, HCl, FTY720
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Form:
solid
Storage condition:
OK to freeze
form
solid
storage condition
OK to freeze
solubility
soluble (DMSO (20 mg/ml) or Ethanol (20 mg/ml))
storage temp.
−20°C
General description
A cell-permeable aminopropanediol immunosuppressive agent that displays lymphocyte sequestration properties. Reported to be phosphorylated by sphingosine kinase to FTY720-P, which has been shown to potently stimulate GTPγS binding activity in S1P-transfected CHO cells (EC50 = 210 pM, 4.9 nM, 4.3 nM, and 1 nM for S1P1, S1P3, S1P4 and S1P5, respectively).
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.