368057
Granzyme B Substrate I, Colorimetric
Colorimetric substrate for the detection of granzyme B and caspase-8 activity.
Synonym(s):
Granzyme B Substrate I, Colorimetric, Ac-IETD- pNA, Caspase-8 Substrate I, Ac-IETD-pNA, Caspase-8 Substrate I
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About This Item
Empirical Formula (Hill Notation):
C27H38N6O12
Molecular Weight:
638.62
NACRES:
NA.77
UNSPSC Code:
12352200
Assay:
≥95% (HPLC)
Form:
lyophilized solid
Quality level:
Storage condition:
OK to freeze, protect from light
Quality Level
assay
≥95% (HPLC)
form
lyophilized solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
white
solubility
DMSO: 5 mg/mL
shipped in
ambient
storage temp.
−20°C
General description
Colorimetric substrate for detection of granzyme B. Cleavage is monitored colorimetrically at ~405 nm.
Colorimetric substrate for the detection of granzyme B and caspase-8 activity. Cleavage of pNA is monitored colorimetrically at ~405 nm.
Biochem/physiol Actions
Cell permeable: no
Primary Target
Colorimetric substrate for the detection of granzyme B and caspase-8 activity
Colorimetric substrate for the detection of granzyme B and caspase-8 activity
Product does not compete with ATP.
Reversible: no
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Other Notes
Ac-Ile-Glu-Thr-Asp-pNA
Koeplinger, K.A., et al. 2000. Protein Exp. Purif. 18, 378.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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