371820
G-Protein βγ Binding Peptide, mSIRK(L9A)
A cell-permeable, single point mutated (Leu⁹ to Ala), N-myristoylated G-protein βγ Binding Peptide (mSIRK).
Synonym(s):
G-Protein βγ Binding Peptide, mSIRK(L9A), mSIRK(L9A), myr-SIRKALNIAGYPDYD-OH
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About This Item
Empirical Formula (Hill Notation):
C90H144N20O25
Molecular Weight:
1906.23
NACRES:
NA.77
UNSPSC Code:
12352202
Assay:
≥95% (HPLC)
Form:
lyophilized solid
Quality level:
Storage condition:
OK to freeze, desiccated (hygroscopic)
Quality Level
assay
≥95% (HPLC)
form
lyophilized solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated (hygroscopic)
color
white
solubility
DMSO: 5 mg/mL
shipped in
ambient
storage temp.
2-8°C
General description
A cell-permeable, N-myristoylated G-Protein Binding Peptide (mSIRK) that contains a single point mutation (Leu9 to Ala). In contrast to mSIRK (Cat. No. 371818), the mutant peptide is unable to enhance ERK1/2 phosphorylation. Useful as a negative control for mSIRK.
A cell-permeable, single point mutated (Leu9 to Ala), N-myristoylated G-protein βγ Binding Peptide (mSIRK). Does not enhance ERK1/2 phosphorylation and serves as a negative control for studies involving mSIRK (Cat. No. 371818).
Biochem/physiol Actions
Cell permeable: yes
Primary Target
G-protein βγ
G-protein βγ
Product does not compete with ATP.
Reversible: no
Packaging
Packaged under inert gas
Physical form
Supplied as a trifluoroacetate salt.
Preparation Note
Following reconstitution aliquot and freeze(-20°C). Stock solutions are stable for up to 4 months at -20°C.
Other Notes
Goubaeva, F., et al. 2003. J. Biol. Chem.278, 19634.
Scott, J.K., et al. 2001. EMBO J.20, 767.
Scott, J.K., et al. 2001. EMBO J.20, 767.
Myr-N-Ser-Ile-Arg-Lys-Ala-Leu-Asn-Ile-Ala-Gly-Tyr-Pro-Asp-Tyr-Asp-OH
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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