Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
UNSPSC Code:
12352202
assay
≥95% (SDS-PAGE and HPLC)
Quality Segment
form
lyophilized
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
impurities
≤0.1 ng/μg Endotoxins (ng/μg IGF-I)
shipped in
wet ice
storage temp.
−20°C
General description
Full-length, recombinant, rat insulin-like growth factor I (IGFI) expressed in E. coli. The IGF-I growth factor regulates proliferation and survival signals through the AKT pathway. This growth hormone is useful in the study of cell proliferation and survival signals.
Biochem/physiol Actions
ED₅₀: <10 ng/ml as determined using a type I IGF receptor binding assay; <30 ng/ml as determined by stimulation of protein synthesis in rat L6 myeloblasts.
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Reconstitute with H₂O to a final concentration of 0.1-1 mg/ml. Further dilute with aqueous buffers before use.
Other Notes
Clark, R.G., et al. 1997. Endocrinology138, 4316.
Tamura, K., et al. 1989. J Biol Chem. 264, 5616.
Tamura, K., et al. 1989. J Biol Chem. 264, 5616.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.