407653
Interleukin-6 Receptor, Soluble, Human, Recombinant, S. frugiperda
Synonym(s):
rhIL-6 sR
Sign In to View Organizational & Contract Pricing.
Select a Size
About This Item
NACRES:
NA.42
UNSPSC Code:
12352202
assay
≥97% (SDS-PAGE)
form
lyophilized
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
impurities
≤1 EU/μg Endotoxin
shipped in
ambient
storage temp.
−70°C
Quality Level
Biochem/physiol Actions
ED₅₀= ≥5 ng/ml as measured by its ability to enhance IL-6-induced growth inhibition of mouse M1 myeloid leukemic cells
Disclaimer
Toxicity: Standard Handling (A)
General description
Recombinant, human soluble interleukin-6 receptor expressed in S. frugiperda insect cells. Soluble form of the IL-6 receptor that binds IL-6 and mediates IL-6 signaling through interaction with gp 130. Elevated serum levels of soluble IL-6 receptors have been shown to be associated with a number of pathological states, including multiple myelomas, adult T cell leukemia, interstitial lung infection, and HIV infection.
Other Notes
Schobitz, B., et al. 1995. FASEB J. 9, 659.
Yokoyama, A., et al. 1995. Clin. Exp. Immunol. 100, 325.
Suzuki, H., et al. 1993. Eur. J. Immunol. 23, 1078.
Lust, J.A., et al. 1992. Cytokine 4, 96.
Sugita, T., et al. 1990. J. Exp. Med. 171, 2001.
Yamasaki, K., et al. 1988. Science241, 825.
Yokoyama, A., et al. 1995. Clin. Exp. Immunol. 100, 325.
Suzuki, H., et al. 1993. Eur. J. Immunol. 23, 1078.
Lust, J.A., et al. 1992. Cytokine 4, 96.
Sugita, T., et al. 1990. J. Exp. Med. 171, 2001.
Yamasaki, K., et al. 1988. Science241, 825.
Physical form
Lyophilized from sterile-filtered PBS, 50 µg BSA/µg IL-6 receptor.
Preparation Note
Reconstitute to a concentration ≥100 µg/ml with sterile PBS containing at least 0.1% HSA or BSA.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Related Content
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service