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Merck

420112

JAK3 Inhibitor, Negative Control - CAS 153437-07-1 - Calbiochem

The JAK3 Inhibitor, Negative Control, also referenced under CAS 153437-07-1, controls the biological activity of JAK3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

Synonym(s):

JAK3 Inhibitor, Negative Control - CAS 153437-07-1 - Calbiochem, 4-Phenylamino-6,7-dimethoxyquinazoline, HCl, WHI-P258, HCl

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About This Item

Empirical Formula (Hill Notation):
C16H15N3O2 · xHCl
CAS Number:
Molecular Weight:
281.31 (free base basis)
UNSPSC Code:
12352200
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Quality Segment

assay

≥92% (HPLC)

form

solid

potency

<300 μM IC50

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, protect from light

color

pale yellow

solubility

DMSO: 5 mg/mL

shipped in

ambient

storage temp.

2-8°C

General description

A useful negative control for JAK3 Inhibitors (Cat. Nos. 420101, 420104, and 420106; IC50 >300 µM).

Biochem/physiol Actions

Cell permeable: no
Primary Target
A negative control for JAK3 inhibitors
Product competes with ATP.
Reversible: no

Packaging

Packaged under inert gas

Preparation Note

Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 1 year at 4°C.

Other Notes

Sudbeck, E.A., et al. 1999. Clin. Cancer Res. 5, 1569.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)


Storage Class

10-13 - German Storage Class 10 to 13



Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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