420118
JNK Inhibitor I, (L)-Form, Cell-Permeable, Negative Control
The JNK Inhibitor I, (L)-Form, Cell-Permeable, Negative Control controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
Synonym(s):
JNK Inhibitor I, (L)-Form, Cell-Permeable, Negative Control, (L)-HIV-TAT48-57-PP, GRKKRRQRRRPP-NH2
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About This Item
Empirical Formula (Hill Notation):
C65H124N34O13
Molecular Weight:
1589.90
UNSPSC Code:
12352200
Assay:
≥97% (HPLC)
Form:
lyophilized solid
Quality level:
Storage condition:
OK to freeze, desiccated (hygroscopic)
Quality Level
assay
≥97% (HPLC)
form
lyophilized solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated (hygroscopic)
solubility
water: 2 mg/mL
shipped in
ambient
storage temp.
−20°C
General description
A highly cell-permeable 10-amino acid carrier peptide derived from HIV-TAT48-57 sequence that is modified with two proline residues. Shown to accumulate into a variety of cells. Serves as a useful negative control for studies involving JNK Inhibitor I, (L)-Form, Cell-Permeable (Cat. No. 420116).
A highly cell-permeable carrier decapeptide derived from HIV-TAT48-57 sequence that is modified with two proline residues. Serves as a useful negative control for studies involving JNK Inhibitor I, (L)-Form, Cell-permeable (Cat. No. 420116).
Biochem/physiol Actions
Cell permeable: yes
Primary Target
A useful negative control for studies involving JNK Inhibitor I, (L)-Form, Cell-Permeable
A useful negative control for studies involving JNK Inhibitor I, (L)-Form, Cell-Permeable
Product does not compete with ATP.
Reversible: no
Packaging
Packaged under inert gas
Physical form
Supplied as a trifluoroacetate salt.
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Other Notes
Bonny, C., et al. 2001. Diabetes50, 77.
Vocero-Akbani, A. M., et al 1999. Nat. Med.5, 29.
Schwarze, S. R., et al. 1999. Science285, 1573.
Nagahara, H., et al. 1998. Nat. Med.4, 1449.
Vives, E., et al. 1997. J. Biol. Chem.272, 16010.
Vocero-Akbani, A. M., et al 1999. Nat. Med.5, 29.
Schwarze, S. R., et al. 1999. Science285, 1573.
Nagahara, H., et al. 1998. Nat. Med.4, 1449.
Vives, E., et al. 1997. J. Biol. Chem.272, 16010.
H-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Pro-Pro-NH₂
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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