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420318

Kainic Acid

Name: Kainic Acid
Brand: MM

≥98% (HPLC), solid, amino acid receptor agonist, Calbiochem^®

Synonym(s):

Kainic Acid, 2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic Acid

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About This Item

Empirical Formula (Hill Notation):

C₁₀H₁₅NO₄

CAS Number:

487-79-6

Molecular Weight:

213.23

MDL number:

MFCD00077806

UNSPSC Code:

12352106

NACRES:

NA.77

Assay:

≥98% (HPLC)

Form:

solid

Storage condition:

OK to freeze

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Properties

Product Name

Kainic Acid, An excitatory amino acid receptor agonist selective for the kainate receptor subtype (K_i = 21 nM for ³H-kainate binding in rat striatum).

Quality Segment

200

description

Merck USA index - 14, 5276

assay

≥98% (HPLC)

form

solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze

color

off-white

solubility

dilute base: 10 mg/mL, water: 10 mg/mL

shipped in

ambient

storage temp.

2-8°C

SMILES string

[N+H2]1[C@@H]([C@H]([C@H](C1)C(=C)C)CC(=O)O)C(=O)[O-]

InChI

1S/C10H15NO4/c1-5(2)7-4-11-9(10(14)15)6(7)3-8(12)13/h6-7,9,11H,1,3-4H2,2H3,(H,12,13)(H,14,15)/t6-,7+,9-/m0/s1

InChI key

VLSMHEGGTFMBBZ-OOZYFLPDSA-N

Description

General description

An excitatory amino acid receptor agonist selective for the kainate receptor subtype (K_i = 21 nM for ³H-kainate binding in rat striatum). Also activates AMPA receptors.

Biochem/physiol Actions

Cell permeable: no

Primary Target
Kainate receptor subtype

Product does not compete with ATP.

Reversible: no

Target K_i: 21 nM for 3H-kainate binding in rat striatum

Other Notes

Niu, L., et al. 1996. Biochemistry35, 2030.
Watkins, J.C. and Evans, R.H. 1981. Annu. Rev. Pharmacol. Toxicol. 21, 165.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Harmful (C)

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c