420318
Kainic Acid
≥98% (HPLC), solid, amino acid receptor agonist, Calbiochem®
Synonym(s):
Kainic Acid, 2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic Acid
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About This Item
Empirical Formula (Hill Notation):
C10H15NO4
CAS Number:
Molecular Weight:
213.23
MDL number:
UNSPSC Code:
12352106
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
solid
Storage condition:
OK to freeze
Product Name
Kainic Acid, An excitatory amino acid receptor agonist selective for the kainate receptor subtype (Ki = 21 nM for ³H-kainate binding in rat striatum).
Quality Segment
description
Merck USA index - 14, 5276
assay
≥98% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
color
off-white
solubility
dilute base: 10 mg/mL, water: 10 mg/mL
shipped in
ambient
storage temp.
2-8°C
SMILES string
[N+H2]1[C@@H]([C@H]([C@H](C1)C(=C)C)CC(=O)O)C(=O)[O-]
InChI
1S/C10H15NO4/c1-5(2)7-4-11-9(10(14)15)6(7)3-8(12)13/h6-7,9,11H,1,3-4H2,2H3,(H,12,13)(H,14,15)/t6-,7+,9-/m0/s1
InChI key
VLSMHEGGTFMBBZ-OOZYFLPDSA-N
General description
An excitatory amino acid receptor agonist selective for the kainate receptor subtype (Ki = 21 nM for 3H-kainate binding in rat striatum). Also activates AMPA receptors.
Biochem/physiol Actions
Cell permeable: no
Primary Target
Kainate receptor subtype
Kainate receptor subtype
Product does not compete with ATP.
Reversible: no
Target Ki: 21 nM for 3H-kainate binding in rat striatum
Other Notes
Niu, L., et al. 1996. Biochemistry35, 2030.
Watkins, J.C. and Evans, R.H. 1981. Annu. Rev. Pharmacol. Toxicol. 21, 165.
Watkins, J.C. and Evans, R.H. 1981. Annu. Rev. Pharmacol. Toxicol. 21, 165.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Harmful (C)
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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