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420323

KT5720

Name: KT5720
Brand: MM

InSolution, ≥95%

Synonym(s):

InSolution KT5720, PKA Inhibitor VII

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About This Item

Empirical Formula (Hill Notation):

C₃₂H₃₁N₃O₅

CAS Number:

108068-98-0

Molecular Weight:

537.61

UNSPSC Code:

12352200

NACRES:

NA.77

MDL number:

MFCD00132118

Assay:

≥95% (HPLC)

Form:

liquid

Storage condition:

OK to freeze, protect from light

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Properties

Quality Segment

100

assay

≥95% (HPLC)

form

liquid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, protect from light

solubility

DMSO: soluble

shipped in

wet ice

storage temp.

−20°C

SMILES string

[n]21c3c4[n](c6c(c4c7c(c3c8c2cccc8)CNC7=O)cccc6)[C@H]5O[C@@]1([C@](C5)(O)C(=O)OCCCCCC)C

InChI

1S/C32H31N3O5/c1-3-4-5-10-15-39-30(37)32(38)16-23-34-21-13-8-6-11-18(21)25-26-20(17-33-29(26)36)24-19-12-7-9-14-22(19)35(28(24)27(25)34)31(32,2)40-23/h6-9,11-14,23,38H,3-5,10,15-17H2,1-2H3,(H,33,36)/t23-,31+,32+/m0/s1

InChI key

ZHEHVZXPFVXKEY-RUAOOFDTSA-N

Description

Biochem/physiol Actions

Cell permeable: yes

Product competes with ATP.

Reversible: yes

Target K_i: 56 nM against protein kinase A

Packaging

Packaged under inert gas

Physical form

A 2 mM (50 µg/47 µl) solution of KT 5720 (Cat. No. 420320) in DMSO.

Preparation Note

Following the initial thaw, aliquot and freeze (20°C).

Other Notes

Simpson, C.S., and Morris, B.J. 1995. Neurosci.68, 97.
Cabell, L, and Audesirk, G. 1993. Int. J. Dev. Neurosci.11, 357.
Gadbois, D.M., et al. 1992. Proc. Natl. Acad. Sci. USA89, 8626.
Kase, H., et al. 1987. Biochem. Biophys. Res. Commun.142, 436.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Irritant (B)

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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

188.6 °F - (refers to pure substance)

flash_point_c

87 °C - (refers to pure substance)

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