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About This Item
UNSPSC Code:
12352201
NACRES:
NA.77
Form:
lyophilized
Storage condition:
OK to freeze
Product Name
Lipopolysaccharide, Ultra pure, Salmonella minnesota R595 (Re), Phenol-petroleum ether extracted lipopolysaccharide (LPS) containing ≤0.3% proteins.
Quality Segment
description
RTECS - UX2990000
form
lyophilized
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
solubility
0.5% triethylamine: 1 mg/mL, water: 1 mg/mL
shipped in
ambient
storage temp.
2-8°C
General description
Phenol-petroleum ether extracted lipopolysaccharide (LPS) containing ≤0.3% proteins. LPS 595 (Re) has been shown to stimulate Toll-like receptor-4 (TLR4), but not TLR2, signaling in human cell lines.
Biochem/physiol Actions
Cell permeable: no
Primary Target
Stimulate Toll-like receptor-4 (TLR4) signaling in human cell lines
Stimulate Toll-like receptor-4 (TLR4) signaling in human cell lines
Product does not compete with ATP.
Reversible: no
Preparation Note
Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 6 months.
Warming to 37°C with intermittent vortexing or sonication may be required to achieve complete solubilization in H₂O.
Other Notes
Hirschfeld, M., et al. 2000. J. Immunol.165, 618.
Tapping, R.I., et al. 2000. J. Immunol.165, 5780.
Galanos, C., et al. 1969. Eur. J. Biochem.9, 245.
Tapping, R.I., et al. 2000. J. Immunol.165, 5780.
Galanos, C., et al. 1969. Eur. J. Biochem.9, 245.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Harmful (C)
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Oral
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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